Evaluating Intestinal Fatty Acid-Binding Protein Levels to Detect Gastrointestinal Involvement in Children with IgA Vasculitis

What this Trial Is About

Researchers are studying children aged 2 to 18 years with IgA vasculitis to see if plasma intestinal fatty acid-binding protein I-FABP levels are linked to gastrointestinal problems. This observational study aims to find out if I-FABP can serve as a useful biomarker to detect gastrointestinal involvement in pediatric IgA vasculitis. The study enrolls children who meet specific classification criteria and follows them over time. During the study, blood samples are taken at diagnosis and again at a routine follow-up visit about 2 to 4 weeks later. Plasma from these samples will be used to measure I-FABP levels. Participants are grouped based on whether they have gastrointestinal symptoms or not. No experimental treatments or devices are given, as all procedures happen during standard care visits with the addition of blood sampling for research purposes. Participants provide clinical, laboratory, and demographic information at the start and follow-up visits. Researchers compare I-FABP levels and clinical data between groups to assess the association with gastrointestinal issues. The study monitors children through routine medical visits and collects data over a few weeks, aiming to identify noninvasive markers that can help detect gastrointestinal involvement early in IgA vasculitis.

I-FABP as a Predictor of Gastrointestinal Involvement in Pediatric IgA Vasculitis