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Factors Associated With Clinical Pregnancy Outcomes in Intrauterine Insemination (IUI) Cycles
Led by Chinese University of Hong Kong · Updated on 2026-05-11
3000
Participants Needed
1
Research Sites
102 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Hypotheses: We hypothesize that variations in hormonal profiles (LH, estradiol, progesterone) during ovarian stimulation, follicular response, endometrial characteristics, and sperm quality parameters are significantly associated with clinical pregnancy outcomes in intrauterine insemination (IUI) cycles. Aims * To investigate the association between hormonal profiles on the trigger day (LH, estradiol, progesterone), follicular response, endometrial thickness, and sperm parameters with clinical pregnancy outcomes in IUI cycles. * To develop and validate a predictive model for clinical pregnancy incorporating key determinants such as female age, hormonal response, endometrial characteristics, and sperm quality. * To compare natural and gonadotropin-stimulated IUI cycles in terms of hormonal profiles, pregnancy outcomes, and cost-effectiveness. Primary Outcome Clinical pregnancy rate (CPR), defined as the presence of a gestational sac with a fetal heartbeat on ultrasound at approximately 6 weeks of gestation following intrauterine insemination. Secondary Outcomes * Biochemical pregnancy rate. * Ongoing pregnancy rate * Live birth rate
CONDITIONS
Official Title
Factors Associated With Clinical Pregnancy Outcomes in Intrauterine Insemination (IUI) Cycles
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Couples who underwent at least one IUI-intrauterine insemination cycle.
You will not qualify if you...
- Couples who used donor sperm.
- Cases with missing core outcome data
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
The Chinese University of Hong Kong
Hong Kong, China
Actively Recruiting
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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