Falls and Functional Impairments in Breast Cancer Patients with Chemotherapy-Induced Peripheral Neuropathy.
Hiroko Komatsu, Kaori Yagasaki, Yasuhiro Komatsu...
https://pubmed.ncbi.nlm.nih.gov/31259221/Actively Recruiting
Led by Texas Woman's University · Updated on 2025-09-03
40
Participants Needed
1
Research Sites
26 weeks
Total Duration
This research focuses on people who had cancer and developed peripheral neuropathy as a side effect of cancer treatments. It aims to understand how this neuropathy affects thinking, feeling, balance, and movement, and how these factors may increase the risk of falls or affect quality of life. The study also looks at the ability to perform two tasks at once, like walking while texting, which may be challenging for those affected. The study compares two groups individuals with a history of non-central nervous system cancer who have peripheral neuropathy symptoms caused by their cancer treatments, and age- and gender-matched individuals without neuropathy symptoms. Researchers assess walking patterns, especially backward walking on a computerized mat, along with cognitive, motor, and sensory abilities to explore their impact on fall risk and quality of life. Participants will undergo various assessments including tests for fall risk, quality of life, cognitive functions like working memory and visual attention, grip strength, lower extremity strength, and balance. These evaluations involve single and dual task walking tests and are designed to identify impairments that may predict fall risk or impact quality of life. The study includes healthy volunteers and will continue until June 2026.
CONDITIONS
Fall Risk and Quality of Life: in Individuals With Cancer Treatment Related Peripheral Neuropathy.
P
Priya Karakkattil
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Texas Woman's University
Lead Sponsor
You may qualify if you...
You will not qualify if you...
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 1 day
Participants complete a series of cognitive, motor, sensory, and gait assessments to evaluate fall risk and quality of life.
1 visit (in-person)
Duration - Up to 6 months
Participants are observed to correlate cognitive, motor, and sensory impairments with fall risk and quality of life over time.
Follow-up assessments may occur depending on study schedule
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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Lead Sponsor