Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
ID06313359

Fall Risk and Quality of Life: Influence of Dual Task Performance, Cognition, and Sensorimotor Variables in Individuals With Cancer Treatment Related Peripheral Neuropathy

Led by Texas Woman's University · Updated on 2025-09-03

40

Participants Needed

1

Research Sites

26 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This research focuses on people who had cancer and developed peripheral neuropathy as a side effect of cancer treatments. It aims to understand how this neuropathy affects thinking, feeling, balance, and movement, and how these factors may increase the risk of falls or affect quality of life. The study also looks at the ability to perform two tasks at once, like walking while texting, which may be challenging for those affected. The study compares two groups: individuals with a history of non-central nervous system cancer who have peripheral neuropathy symptoms caused by their cancer treatments, and age- and gender-matched individuals without neuropathy symptoms. Researchers assess walking patterns, especially backward walking on a computerized mat, along with cognitive, motor, and sensory abilities to explore their impact on fall risk and quality of life. Participants will undergo various assessments including tests for fall risk, quality of life, cognitive functions like working memory and visual attention, grip strength, lower extremity strength, and balance. These evaluations involve single and dual task walking tests and are designed to identify impairments that may predict fall risk or impact quality of life. The study includes healthy volunteers and will continue until June 2026.

CONDITIONS

Brief Title

Fall Risk and Quality of Life: in Individuals With Cancer Treatment Related Peripheral Neuropathy.

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Individuals 18 years and older
  • Diagnosed with non-CNS cancer and have peripheral neuropathy symptoms from cancer treatment
  • Age- and gender-matched individuals without peripheral neuropathy symptoms
  • No diagnosed cognitive symptoms for control group
  • Able to walk independently without assistive device
  • Able to use a phone to send text messages
  • Able to understand and speak English
Not Eligible

You will not qualify if you...

  • Unable to follow two-step commands
  • Unable to walk 50 feet independently without an assistive device
  • Unable to use a phone to send text messages
  • Diagnosis of diabetic peripheral neuropathy
  • Diagnosis of central nervous system cancer
  • Unable to speak or understand English

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - 1 day

Participants complete a series of cognitive, motor, sensory, and gait assessments to evaluate fall risk and quality of life.

1 visit (in-person)

Long-term Monitoring

Duration - Up to 6 months

Participants are observed to correlate cognitive, motor, and sensory impairments with fall risk and quality of life over time.

Follow-up assessments may occur depending on study schedule

Trial Site Locations

Total: 1 location

1

Texas Woman's University

Dallas, Texas, United States, 75235

Actively Recruiting

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Research Team

P

Priya Karakkattil

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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Frequently Asked Questions

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Published Research Related To This Trial

Dual-task gait speed assessments with an electronic walkway and a stopwatch in older adults. A reliability study.

M Montero-Odasso, Y Sarquis-Adamson, N Kamkar...

https://pubmed.ncbi.nlm.nih.gov/33017671