Study of Early Movement Patterns to Predict Neurodevelopmental Outcomes in Infants at Risk of Cerebral Palsy

What this Trial Is About

Researchers are studying infants with and without medical complexities to improve early detection of neurodevelopmental impairments, especially cerebral palsy CP. The study aims to find the best time to use the Prechtl General Movement Assessment GMA to predict developmental outcomes by age two. The study plans to enroll 350 infants, including 100 healthy term-born babies and 250 at risk for CP, and involves multiple research teams across several institutions. Families will use the Baby Moves app to record videos of their infants at specific ages 10, 12, 14, 16, 18, and 20 weeks corrected age. These videos are reviewed by trained assessors using the Prechtl GMA method to identify movement patterns. If an infants movements are considered high risk, families receive a follow-up virtual visit with developmental assessments. Infants may also be referred to early intervention services. Data is securely stored in REDCap databases managed across participating sites. Participants will be followed for five years, with developmental assessments at one and two years of age, including standardized tests like the Bayley Scales and questionnaires about quality of life and behavior. Families will complete surveys about the Baby Moves app and participate in phone follow-ups. Researchers will measure fidgety movements at 4 months and neurodevelopmental outcomes at 2 years, tracking diagnoses and developmental progress. The study collects comprehensive medical and developmental data to improve early detection methods.

Families Filming Infants Learning Movement