Actively Recruiting
A Family Centred Approach to Enhance Lifestyle Change and Behavioural Modification for Prevention of Cardiovascular Diseases Among Adolescents and Their Families in Uganda
Led by MRC/UVRI and LSHTM Uganda Research Unit · Updated on 2025-12-12
1280
Participants Needed
2
Research Sites
52 weeks
Total Duration
On this page
Sponsors
M
MRC/UVRI and LSHTM Uganda Research Unit
Lead Sponsor
U
University of California
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are evaluating a family-centred approach to prevent cardiovascular diseases (CVD) among adolescents and their families in Uganda. This 5-year study focuses on reducing risk factors like unhealthy diet and physical inactivity that contribute to CVD and other non-communicable diseases (NCDs). The study adapts a proven intervention from Asia to the Ugandan context, aiming to support healthier lifestyle behaviors during the critical adolescence period when habits form that affect adult health. The study includes two groups: one receiving the FaCe-D intervention, which involves home visits by Village Health Teams delivering diet, physical activity, and health messaging; and a control group receiving standard care with usual health promotion activities. The study is divided into three phases: adapting the intervention, implementing it, and evaluating its effectiveness and feasibility in 32 villages. Participants will be involved for at least 12 months, during which researchers will assess changes in cardiovascular health and sleep quality. Evaluations include monitoring behavior changes, health outcomes, and implementation costs. The study also considers adoption and feasibility to understand how well the intervention works in real community settings.
CONDITIONS
Brief Title
A Family-centred Approach Enhancing Cardiovascular Health in Ugandan Adolescents and Their Families
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 10 to 19 years
- Household head or parent has provided consent or permission
- Planning to continue living in the study village for the next 12 months
You will not qualify if you...
- Attending or planning to attend a boarding school
- Pregnant or lactating
- Known chronic condition such as mental illness
- Adolescent does not assent or consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 12 months
Participants receive a family-centred behavioral intervention focused on diet, physical activity, and health messaging delivered by Village Health Teams to promote lifestyle changes and reduce cardiovascular risk.
Regular home visits by Village Health Teams throughout the intervention period
Duration - 12 months
Participants in the control arm continue to receive standard care involving quarterly visits by Village Health Teams for general health promotion and monitoring as per Ministry of Health guidelines.
Quarterly visits by Village Health Teams
Trial Site Locations
Total: 2 locations
1
TASO Jinja
Jinja, Uganda
Actively Recruiting
2
Kiswa Health center III
Kampala, Uganda
Actively Recruiting
Research Team
A
Arthur Namara, MSc
C
Chairperson, UVRI REC, PhD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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