Actively Recruiting

FEMALE
Healthy Volunteers
NCT07387653

Feasibility and Clinical Utility of Paired Non-Invasive Hemodynamic and Tissue Oximetry Monitoring to Detect Limb Ischemia in Lithotomy-Positioned Surgeries

Led by The University of Texas Health Science Center, Houston · Updated on 2026-05-14

30

Participants Needed

2

Research Sites

43 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The LIMB Study is a prospective, observational pilot study evaluating the feasibility of combined non-invasive hemodynamic and lower-limb tissue oximetry monitoring during prolonged minimally invasive pelvic surgeries performed in lithotomy position. Thirty patients will undergo continuous intraoperative monitoring, with the primary outcome being the frequency and duration of tissue oxygen desaturation events and secondary outcomes examining correlations with postoperative limb pain, sensation, and motor function. The study is non-interventional, poses minimal risk, and aims to generate preliminary data to inform future strategies for early detection and prevention of limb ischemia and well-leg compartment syndrome

CONDITIONS

Official Title

Feasibility and Clinical Utility of Paired Non-Invasive Hemodynamic and Tissue Oximetry Monitoring to Detect Limb Ischemia in Lithotomy-Positioned Surgeries

Who Can Participate

FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patients
  • Undergoing minimally invasive pelvic surgery such as hysterectomy, myomectomy, or endometriosis surgery
  • Surgery performed in lithotomy position
  • Expected surgical duration > 2 hours as determined by the primary surgeon
Not Eligible

You will not qualify if you...

  • Pregnant patients
  • Procedures expected to last < 2 hours
  • Open surgical approaches
  • Minor procedures
  • Known allergy or sensitivity to adhesives used for monitoring sensors
  • Vulnerable populations such as incarcerated, elderly, or pregnant individuals

AI-Screening

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Trial Site Locations

Total: 2 locations

1

Memorial Hermann Medical Center

Houston, Texas, United States, 77027

Not Yet Recruiting

2

Memorial Hermann Hospital

Houston, Texas, United States, 77401

Actively Recruiting

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Research Team

R

Randa Jalloul, MD, MS

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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