FEMART-1 Pilot Study Evaluating Prehospital Femoral Arterial Sheath Placement for Invasive Blood Pressure Monitoring in Non-Traumatic Out-of-Hospital Cardiac Arrest Patients Aged 18 to 70 Years

What this Trial Is About

The trial investigates patients who experience non-traumatic out-of-hospital cardiac arrest OHCA and aims to study the feasibility, safety, and timing of placing a femoral arterial sheath before they reach the hospital. This procedure allows invasive arterial blood pressure monitoring to manage blood flow and medication more precisely during emergency care. Researchers hope this approach helps prevent low blood pressure and repeated cardiac arrests, potentially improving organ function and neurological outcomes after the event. Participants receive either standard advanced emergency resuscitation and post-resuscitation care with ultrasound-guided femoral arterial sheath placement for blood pressure monitoring and possible support for ECMO treatment if needed, or standard care without the sheath insertion. The study evaluates these two groups during prehospital care until hospital arrival, focusing on procedural success, safety, and timing. During the study, researchers monitor the success of arterial blood pressure measurement, any procedure-related complications, and how quickly the sheath is placed. They also record use of medications to support heart function, rates of repeated cardiac arrest before and just after hospital arrival, blood pressure and heart rate at hospital handover, blood lactate levels, and survival with neurological outcomes up to 30 days after the event. Participation lasts from emergency care through hospital admission and early follow-up.

FEMART-1 Pilot Study