Clinical features of metastatic bone disease and risk of skeletal morbidity.
Robert E Coleman
https://pubmed.ncbi.nlm.nih.gov/17062708/Actively Recruiting
Led by Costantino Errani · Updated on 2025-12-15
250
Participants Needed
1
Research Sites
N/A
Total Duration
Researchers are reviewing medical records, radiological images, and histological data of approximately 750 patients treated for bone metastases from carcinoma at the Rizzoli Orthopaedic Institute between January 1, 2010, and December 31, 2022. This observational study aims to generate synthetic patient data to evaluate fracture risk related to bone metastases from various carcinomas. The study involves analyzing and reviewing existing clinical and imaging data from these patients without administering new treatments. It focuses on patients diagnosed with bone metastases regardless of carcinoma type, number, or location of metastases. The primary goal is to create a comprehensive dataset of clinical information and diagnostic images collected at baseline. Participants involvement consists of data review and analysis based on available records and follow-up information from the last 12 months after diagnosis. Researchers will measure outcomes by compiling this dataset for risk evaluation. Since this is a retrospective observational study, no direct interventions or additional visits are required from participants. The study is expected to continue through December 2026.
CONDITIONS
Fracture Risk Evaluation of Bone Metastases Derived From Carcinoma
C
Costantino Errani, MD
R
Roberta Laranga, PhD
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Costantino Errani
Lead Sponsor
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Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Baseline (Day 0)
Participants undergo review and analysis of imaging and clinical data related to bone metastases derived from carcinoma.
1 visit (in-person)
Duration - Up to 12 months
Participants are observed with at least one follow-up visit within 12 months from diagnosis to monitor clinical status and outcomes.
At least 1 follow-up visit
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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Robert E Coleman
https://pubmed.ncbi.nlm.nih.gov/17062708/Hilton Mirels
https://pubmed.ncbi.nlm.nih.gov/14600587/Costantino Errani
Lead Sponsor