The Relationship Between Frailty and Decreased Physical Performance With Death on the Kidney Transplant Waiting List.
Elizabeth C Lorenz, Fernando G Cosio, Shari L Bernard...
https://pubmed.ncbi.nlm.nih.gov/30879429Actively Recruiting
Phase Not Applicable
Age: 18Years +
All Genders
ID07181096
Study of Frailty Among Renal Transplant Recipients and Its Relation to Chronic Renal Allograft Dysfunction
Led by Alexandria University · Updated on 2025-09-18
80
Participants Needed
1
Research Sites
4 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying frailty among patients who have received kidney transplants at Alexandria University Hospitals. The study aims to understand how common frailty is in this group and to explore the connection between frailty and chronic problems with the transplanted kidney. Frailty is linked to factors like diabetes, low serum albumin levels, cognitive impairment, and reduced muscle mass in people with kidney disease. Participants will undergo several assessments including the Clinical Frailty Scale to evaluate frailty, the Patient Generated Subjective Global Assessment to check nutritional status, the Charlson comorbidity score to determine other health conditions, a six-minute walk test to measure physical endurance, and muscle strength measurement using a hand grip strength dynamometer. This is a prospective cross-sectional study involving 80 kidney transplant patients. During the study, participants will be evaluated within 30 days for frailty, nutritional status, comorbidity, and muscle strength. Researchers will use these assessments to better understand how frailty affects kidney transplant recipients and its relationship to chronic kidney transplant dysfunction. The study involves no treatment but focuses on diagnostic tests and physical assessments under medical supervision.
CONDITIONS
Brief Title
Frailty Among Renal Transplant Recipients and Relation to Chronic Allograft Dysfunction
Who Can Participate
Age: 18Years +
All Genders
Eligibility Criteria
You may qualify if you...
- Renal transplanted patients with GFR more than 30
- Adults aged 18 years or older
You will not qualify if you...
- Mentally or physically unfit patients
- Amputation of lower limb
- Active neoplasia, chronic liver disease, previous immunological disease
- Psychiatric disorders
- Pregnancy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Diagnostic Evaluation
Duration - Up to 30 days
Participants undergo assessments including frailty evaluation, nutritional status, comorbidity, six-minute walk test, and muscle strength measurement.
1 visit (in-person)
Trial Site Locations
Total: 1 location
1
Faculty of Medicine, Aexandria University
Alexandria, Egypt, 21526
Actively Recruiting
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Research Team
M
Mohamed mamdouh Elsayed, MD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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Published Research Related To This Trial
Frailty in kidney transplantation: a review on its evaluation, variation and long-term impact.
Carlo Alfieri, Silvia Malvica, Matteo Cesari...
https://pubmed.ncbi.nlm.nih.gov/36325001Frailty and Kidney Transplantation: A Systematic Review and Meta-analysis.
Evelien E Quint, Donika Zogaj, Louise B D Banning...
https://pubmed.ncbi.nlm.nih.gov/34036171