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Frailty in Hip Fracture Patients Treated With Surgery; the Role of Simple Inflammatory Biomarkers. An Observational Study
Led by University of Thessaly · Updated on 2026-05-05
200
Participants Needed
2
Research Sites
6 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Frailty is a common condition among elderly patients who have hip fractures and is linked to worse outcomes. Researchers are studying whether hip fracture patients who have frailty show higher levels of inflammation based on simple blood tests measuring inflammatory biomarkers. This observational study aims to understand the relationship between frailty and inflammation in this group of patients. The study observes hip fracture patients who are treated with surgery. Frailty will be assessed using the Groningen Frailty Indicator, a validated tool. No experimental treatments are given; rather, the study collects data on patients' frailty status and inflammatory markers before surgery to explore possible links. Participants will be evaluated before their surgery with assessments of their frailty status and blood tests for inflammatory biomarkers. Researchers will gather information on these markers and frailty to analyze potential associations. The study is observational, so patients continue their usual care while data is collected. Participation involves preoperative assessments with no additional treatments or interventions required.
CONDITIONS
Brief Title
Frailty, Hip Fractures and Inflammatory Biomarkers
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age greater than 65 years
- ASA Physical Status classification I to III
- Not living in an institution
- Able to communicate effectively
- Patients with hip fractures treated with surgery
You will not qualify if you...
- Severe cognitive dysfunction
- Patients treated without surgery (conservatively)
- Patients with pathological fractures
- Patients who refuse to participate
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Preoperative period
Participants undergo assessments including frailty status and inflammatory biomarker measurements before surgery.
1 visit (in-person)
Duration - Hospital stay duration
Participants receive surgery for hip fracture and immediate post-operative care.
Duration - Up to study completion in 2027
Participants are monitored after surgery to observe recovery and outcomes related to frailty and inflammatory biomarkers.
Trial Site Locations
Total: 2 locations
1
Larissa University Hospital
Larissa, Thessaly, Greece, 41110
Actively Recruiting
2
UHL
Larissa, Thessaly, Greece, 41110
Actively Recruiting
Research Team
E
Eleni Arnaoutoglou, Professor
M
Maria Ntalouka, MD, PhD, MSc
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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