Actively Recruiting
Evaluation of Frailty, Physical Capacity and Lung Function in Postoperative Pulmonary Endarterectomy Patients: an Observational and Prospective Clinical Study
Led by University of Sao Paulo General Hospital · Updated on 2025-03-28
50
Participants Needed
1
Research Sites
56 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to study changes in physical performance, lung function, and muscle strength in patients undergoing pulmonary endarterectomy (PET). It focuses on observing these changes during the postoperative period to better understand the effects of the surgery on physical capacity, lung health, and frailty. The study is observational and prospective, including adults aged 18 and older. Participants will be evaluated at multiple time points: one day before surgery, immediately after discharge from the intensive care unit, before hospital discharge (about 20 days after surgery), and six months post-surgery. Assessments include tests such as the Six-Minute Walk Test, Short Physical Performance Battery, One-Minute Sit-to-Stand Test, manovacuometry, dynamometry, spirometry, and the Clinical Frailty Scale. These tests measure physical performance, muscle strength, lung function, and frailty. During the study, participants will undergo several evaluations at specified time points to track changes in their physical and respiratory health. Researchers will collect data on muscle strength, lung function, and frailty using functional tests and clinical scales. The study also explores risk factors that might predict functional loss during hospitalization. Participants will be monitored over approximately six months to assess recovery and long-term outcomes.
CONDITIONS
Brief Title
Frailty, Physical Capacity and Lung Function in Postoperative Pulmonary Endarterectomy Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 218 years or older
- Both genders
- Scheduled for elective pulmonary endarterectomy surgery
- No cognitive or peripheral motor impairment preventing functional tests before surgery
You will not qualify if you...
- Undergoing reoperation for any reason
- Cognitive or peripheral motor impairment preventing functional tests after surgery
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 1 day
Participants undergo baseline assessments one day before surgery to evaluate physical performance, muscle strength, lung function, and frailty.
1 visit (in-person)
Duration - Up to hospital discharge (approximately 20 days)
Participants undergo pulmonary endarterectomy surgery followed by immediate post-ICU discharge assessments to measure changes in physical and lung function.
2 visits (immediately after ICU discharge and before hospital discharge)
Duration - 6 months post-surgery
Participants are assessed six months after surgery to monitor long-term changes in physical capacity, lung function, and frailty.
1 visit (in-person)
Trial Site Locations
Total: 1 location
1
Instituto do Coração - Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
São Paulo, São Paulo, Brazil, 05403-000
Actively Recruiting
Research Team
R
Rafael M Ianotti, PT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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