Actively Recruiting
Functional Recovery After Total Knee Arthroplasty Comparing Robotic-Assisted and Manual Procedures
Led by University of Pittsburgh · Updated on 2025-12-11
30
Participants Needed
1
Research Sites
52 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to understand how patients recover functionally after total knee arthroplasty (TKA), comparing robotic-assisted procedures to conventional manual ones. It focuses on whether robotic assistance leads to better perceived and actual functional recovery, including for revision and primary TKAs. The study combines patient-reported outcomes, functional tests, kinematic data, and wearable device information to provide a detailed timeline of recovery speed. Participants receive either robotic-assisted or manual total knee arthroplasty, either as a primary or revision procedure. There are four groups: manual revision TKA, robotic-assisted revision TKA, manual primary TKA, and robotic-assisted primary TKA. Each participant undergoes six evaluation sessions: one before surgery and five after surgery at 2 weeks, 6 weeks, 3 months, 6 months, and 1 year, with tests lasting about one hour at a physical therapy research center. During each visit, participants complete several questionnaires about joint function and quality of life, including Forgotten Joint, Promis 29, KOOS, and SF-36. They also perform functional tests such as Timed Up and Go (TUG), walking speed tests, stair climb, balance tests, and others. Researchers may record video to track progress. The main outcomes measured include various timed and distance walking tests at all evaluation points to assess recovery over time.
CONDITIONS
Brief Title
Functional Recovery After Total Knee Arthroplasty
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Candidate for total knee arthroplasty (TKA)
- Able to speak English and understand study instructions
- Have medical clearance from primary care provider, principal investigator, or co-investigator
- Willing to follow all study procedures and be available for the full study duration
You will not qualify if you...
- Experienced two or more falls in the past year
- Unable to walk 100 feet without an assistive device or rest
- Currently have an acute illness
- History of cardiovascular disease or uncontrolled hypertension
- Severe vision impairment
- Have a lower-extremity amputation
- Neurological, muscular, systemic, or connective tissue disorders affecting lower limb function
- Pregnant
- Have a terminal illness
- Plan to have another joint replacement during the study period
- Plan to relocate away from the study area during the study period
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person) for consent and eligibility assessment
Duration - Anytime pre-operatively (baseline)
Participants undergo baseline functional tests and patient reported outcome questionnaires before surgery.
1 baseline visit (in-person, approximately 1 hour)
Duration - Day of surgery plus immediate recovery period
Participants receive either robotic-assisted or manual total knee arthroplasty (primary or revision).
Surgery visit plus immediate post-operative care
Duration - Up to 1 year post surgery
Participants complete functional and patient reported outcome assessments at multiple timepoints to monitor recovery progress.
5 follow-up visits at 2 weeks, 6 weeks, 3 months, 6 months, and 1 year post surgery (in-person, approximately 1 hour each)
Trial Site Locations
Total: 1 location
1
University of Pittsburgh
Pittsburgh, Pennsylvania, United States, 15213
Actively Recruiting
Research Team
V
Victoria Wong, BA
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
4
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