Actively Recruiting

All Genders
ID06722222

A New Surgical Method for Treating Tandem Carotid Lesions: Gao's Triple Eversion Carotid Endarterectomy

Led by Second Affiliated Hospital, School of Medicine, Zhejiang University · Updated on 2024-12-13

11

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating a new surgical method called Gao's triple eversion carotid endarterectomy (GTE-CEA) for treating tandem carotid lesions (TCLs), which involve severe narrowing or blockage in multiple areas of the carotid artery. This innovative procedure aims to address limitations of conventional carotid endarterectomy, which cannot effectively treat all types of TCLs. The study involves a retrospective review of patients who underwent GTE-CEA performed by the same vascular surgeons since September 17, 2021. The GTE-CEA procedure involves exposing the carotid arteries and carefully removing the plaque through a series of eversion steps. Surgeons raise blood pressure and use heparin during the operation to manage blood flow and prevent clots. The arteries are blocked and cut in specific locations to allow plaque removal from the internal and external carotid arteries as well as the common carotid artery. The plaque and debris are thoroughly cleaned using heparin irrigation before completing the procedure. Participants in this study had their medical charts reviewed to assess outcomes and safety, focusing on treatment-related adverse events over an average of three years. Patients underwent digital subtraction angiography or computed tomography angiography before surgery to confirm the severity of carotid artery stenosis. Researchers will monitor adverse events and long-term safety to evaluate the procedure. The study excludes patients who do not meet diagnostic criteria or have less severe stenosis or other artery blockages.

CONDITIONS

Brief Title

Gao's Triple Eversion Carotid Endarterectomy

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Meet the diagnostic criteria for tandem carotid lesion stenosis
  • Have at least 70% asymptomatic stenosis in the common carotid artery or internal carotid artery, or over 50% symptomatic carotid artery stenosis confirmed by digital subtraction angiography or computed tomography angiography before surgery
Not Eligible

You will not qualify if you...

  • Do not meet the diagnostic criteria for carotid artery stenosis
  • Have asymptomatic carotid artery stenosis less than 50% confirmed by imaging before surgery
  • Have stenosis at the opening of the common carotid artery

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Surgery and Immediate Post-operative Care

Duration - Day of surgery and immediate recovery period

Participants undergo Gao's triple eversion carotid endarterectomy, a surgical procedure to treat tandem carotid lesions followed by immediate post-operative care.

1 surgical visit and immediate post-operative monitoring

Long-term Monitoring

Duration - Up to 3 years

Participants are monitored for treatment-related adverse events and recovery over an average of 3 years after surgery.

Periodic follow-up visits as scheduled by the study team

Trial Site Locations

Total: 1 location

1

the Second Affiliated Hospital of Zhejiang University School of Medicine

Hangzhou, Zhejiang, China, 310050

Actively Recruiting

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Research Team

J

Jinren Zhou, Dr.

Z

Zhiwei Gao, Dr.

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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Published Research Related To This Trial

Management and outcome of patients with acute ischemic stroke and tandem carotid occlusion in the ESCAPE-NA1 trial.

Martha Marko, Petra Cimflova, Alexandre Y Poppe...

https://pubmed.ncbi.nlm.nih.gov/33947770

Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials.

Mayank Goyal, Bijoy K Menon, Wim H van Zwam...

https://pubmed.ncbi.nlm.nih.gov/26898852

Acute ischemic stroke with tandem lesions: technical endovascular management and clinical outcomes from the ESCAPE trial.

Zarina Assis, Bijoy K Menon, Mayank Goyal...

https://pubmed.ncbi.nlm.nih.gov/29021311

Emergent Carotid Stenting Plus Thrombectomy After Thrombolysis in Tandem Strokes: Analysis of the TITAN Registry.

Mohammad Anadani, Alejandro M. Spiotta, Ali Alawieh...

https://pubmed.ncbi.nlm.nih.gov/31577899

Simultaneous treatment of common carotid lesions increases the risk of stroke and death after carotid artery stenting.

Charles DeCarlo, Adam Tanious, Laura T Boitano...

https://pubmed.ncbi.nlm.nih.gov/33545307