Actively Recruiting
A Real-World Study on Ultrasound-Based Screening and Integrated Therapeutic Strategies for Patients With Concomitant Coronary and Cervicocephalic Artery Stenosis
Led by Beijing Anzhen Hospital · Updated on 2025-06-24
1000
Participants Needed
1
Research Sites
47 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study focuses on patients with coronary artery disease (CAD) who are undergoing or scheduled for percutaneous coronary intervention (PCI). It aims to understand how common and significant head and neck arterial narrowing (stenosis) is in these patients. Researchers will explore how different combined treatment approaches affect patient health, using real-world data to improve care for those with both heart and brain blood vessel diseases. The study observes three patient groups: those receiving both PCI and carotid artery treatment, those who have PCI with no or untreated carotid stenosis, and those managed with observation only without PCI or carotid intervention. Doppler ultrasound is used as the main screening tool to assess artery narrowing. Patients are followed under their usual care without additional experimental treatments. Participants will have their artery conditions checked at baseline, with health outcomes tracked over time through measures like the modified Rankin Scale (mRS) and rates of cardiovascular and cerebrovascular events. These assessments occur shortly after treatment and continue for up to a year to monitor both short- and long-term complications. The total duration depends on the follow-up period after initial hospitalization and treatment.
CONDITIONS
Brief Title
A Real-World Study on Ultrasound-Based Screening and Integrated Therapeutic Strategies for Patients With Concomitant Coronary and Cervicocephalic Artery Stenosis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Diagnosed with coronary artery disease
- Scheduled for elective percutaneous coronary intervention (PCI) the following day
You will not qualify if you...
- Expected survival less than 1 year
- Presence of other serious diseases
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - At baseline (prior to or during initial hospitalization)
Participants undergo ultrasound-based screening to assess the presence and severity of coronary and cervicocephalic artery stenosis.
1 baseline visit (in-person)
Duration - Varies based on individual treatment plans during hospitalization and follow-up period
Participants receive routine care which may include percutaneous coronary intervention (PCI), carotid artery stenting, or clinical observation depending on their condition and clinical evaluation.
1 to 2 intervention visits depending on treatment; additional observation visits as needed
Duration - Up to 1 year after initial intervention or observation
Participants are monitored for cardiovascular and cerebrovascular events, complications, and functional outcomes after treatment or observation.
Visits at approximately 7 days, 90 days, and 365 days post baseline
Trial Site Locations
Total: 1 location
1
Beijing Anzhen Hospital
Beijing, China
Actively Recruiting
Research Team
X
Xiaochuan Huo, M.D.
X
Xin Tong, M.D.
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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