Actively Recruiting

Phase Not Applicable
All Genders
NCT04760522

Genome-based Management of Patients in Precision Medicine (Ge-Med) Towards a Genomic Health Program

Led by University Hospital Tuebingen · Updated on 2023-11-29

12000

Participants Needed

1

Research Sites

317 weeks

Total Duration

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AI-Summary

What this Trial Is About

The GE-MED APPROACH project will enroll patients (n = appr. 12.000) with unclear molecular cause of the disease, suspected genetic cause of the disease without detailed molecular analysis like Whole Exome Sequencing (WES). The novelty of this study is to integrate genomic health concepts into immediate clinical care. To achieve these goals, a novel structure for the Triple P (3P) concept of personalized medicine (Personalized, Predictive, Preventive) integrated into a well-established health care system and associated with novel decentralized Disease Analysing Task Forces (DATF) will be implemented. The overall goal of this study is to implement, for the first time, Whole Genome Sequencing (WGS) analysis as a first line diagnostic test for all clinical indications such as Rare Disease (RD )and familial cancer syndromes.

CONDITIONS

Official Title

Genome-based Management of Patients in Precision Medicine (Ge-Med) Towards a Genomic Health Program

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Unclear molecular cause of the disease
  • Suspected genetic cause of the disease
Not Eligible

You will not qualify if you...

  • Missing informed consent of the patient and if applicable the legal representative
  • Previously performed WES or panel analysis

AI-Screening

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Trial Site Locations

Total: 1 location

1

University Hospital Tübingen

Tübingen, Germany, 72076

Actively Recruiting

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Research Team

O

Olaf Rieß, Prof. Dr.

CONTACT

A

Andreas Dufke, PD Dr.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

BASIC_SCIENCE

Number of Arms

1

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