Predictive Value of Glycemic Markers for Gestational Diabetes and Pregnancy Complications in Women With Prior Bariatric Surgery Who Cannot Tolerate Oral Glucose Testing

What this Trial Is About

Gestational diabetes mellitus (GDM) is a common complication during pregnancy that can lead to serious health problems for both mother and baby. This research focuses on pregnant women aged 18 to 50 years who have previously undergone bariatric surgery. The study aims to find out if common blood and urine sugar tests taken during pregnancy can help predict GDM and related complications like large birth weight and excess amniotic fluid, especially in women who have difficulty tolerating the standard glucose test due to side effects from their surgery. Participants will be grouped based on their ability to tolerate the standard 75-gram oral glucose tolerance test (OGTT). Those who complete the OGTT will be compared to those who cannot tolerate or refuse it. Researchers will measure fasting blood sugar, blood sugar after meals, HbA1c, and urine glucose levels during pregnancy. Ultrasound scans in the second and third trimesters will also be performed to assess pregnancy progress and potential complications. Throughout the pregnancy, participants will have routine blood and urine tests, ultrasound scans, and clinical follow-ups until delivery. Researchers will observe the development of GDM between 24 and 28 weeks of pregnancy and monitor for complications like polyhydramnios until birth. Statistical analysis will evaluate how well these routine glycemic markers predict GDM and other pregnancy outcomes in this specific group of women.

Glycemic Markers for Predicting Gestational Diabetes in Pregnant Women With Previous Bariatric Surgery