Actively Recruiting
HEPA, PM2.5, and Cardiometabolic Health
Led by University of Southern California · Updated on 2025-08-01
52
Participants Needed
1
Research Sites
198 weeks
Total Duration
On this page
Sponsors
U
University of Southern California
Lead Sponsor
D
Duke University
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this randomized, double-blind, crossover trial is to test the hypothesis that a longer-term indoor HEPA filtration intervention can improve cardiometabolic profiles by reducing indoor PM2.5 exposures in at-risk individuals.
CONDITIONS
Official Title
HEPA, PM2.5, and Cardiometabolic Health
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 65 and 84 years old
- Nonsmoker for at least 1 year
- History of BMI 65 25 kg/m2 in the past based on medical records
- English or Spanish speaker
- Live in Los Angeles County
You will not qualify if you...
- History of diabetes (type 1 or type 2) or degenerative nervous system disease (Alzheimer's or dementia)
- Currently undergoing active cancer treatment
- Home already has HEPA filters
- Planning to move from current home within 2 years
- Will spend more than one month living outside the primary home
- Health conditions preventing collection of data or biospecimens
- Home not suitable for setting up air purifiers and pollution monitors
- High blood glucose (> 200 mg/dL) from finger stick test
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Keck School of Medicine, University of Southern California
Los Angeles, California, United States, 90033
Actively Recruiting
Research Team
Z
Zhanghua Chen, PhD
CONTACT
J
Junfeng Zhang, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
PREVENTION
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here