Actively Recruiting
Home Exercise for Individuals with Neurodegenerative Disease
Led by Hugo W. Moser Research Institute at Kennedy Krieger, Inc. · Updated on 2025-03-10
30
Participants Needed
1
Research Sites
232 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The primary goal of this study is to address the need for targeted therapeutic interventions for impairments that impact walking in related neurodegenerative diseases.
CONDITIONS
Official Title
Home Exercise for Individuals with Neurodegenerative Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Males with X-linked adrenoleukodystrophy confirmed by biochemical or genetic testing
- Females with X-linked adrenoleukodystrophy confirmed by biochemical testing, genetic testing, or pedigree analysis
- Diagnosis of Leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation confirmed by DARS2 genetic mutation
- Diagnosis of cerebellar ataxia or cerebellar damage from stroke, tumor, or degeneration; genetically confirmed cerebellar disorder with genetic testing provided
- Patients with other similar neurodegenerative diseases confirmed by chart review and clinical exam
- Able to stand for 30 seconds without upper extremity support
- Ambulatory, including use of cane or walker
- Able to walk for 2 minutes
You will not qualify if you...
- Medical or psychological conditions that would interfere with study participation or safe exercise, including uncontrolled hypertension, orthopedic conditions, diabetes, seizure disorder, peripheral vestibular loss, severe aphasia, dementia, or pregnancy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Kennedy Krieger Institute
Baltimore, Maryland, United States, 21205
Actively Recruiting
Research Team
J
Jennifer L Keller, PT, MS
CONTACT
A
Amena Smith Fine, MD PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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