Actively Recruiting
Hyperthyroidism in the Immediate Post-Kidney Transplant Period as a Potential Predictor of Worse Renal Graft Outcome
Led by IRCCS Azienda Ospedaliero-Universitaria di Bologna · Updated on 2025-01-27
100
Participants Needed
1
Research Sites
147 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying the possible link between changes in thyroid function right after kidney transplantation and the success of the transplant. They aim to find out if thyroid problems shortly after surgery affect kidney function, medical complications, or patient survival three months later. The study also seeks to identify factors that might increase the risk of thyroid disorders in this early post-transplant period. Participants are kidney transplant patients whose thyroid function will be monitored immediately after surgery and up to three months later. The study observes how treatments, including immunosuppressants and corticosteroids, may influence thyroid hormone levels. The research focuses on changes caused by surgery stress and exposure to iodine-containing substances. Data will be collected on thyroid function, kidney function, medical complications, and survival outcomes. Participants will be followed from surgery through discharge and up to three months post-transplant. Researchers will measure thyroid and kidney function at baseline and follow-up visits, track any medical complications, and monitor survival. Clinical and laboratory data on thyroid hormone trends within 30 days after transplant will be collected. The study plans to include about 100 patients who meet inclusion criteria and provide informed consent.
CONDITIONS
Official Title
Hyperthyroidism as a Potential Predictive of Worse Outcome of Renal Graft
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Transplanted at the study's transplant center
- Available 3-month follow-up data
- Age 18 years or older
- Clinical and laboratory data on thyroid function trends within 30 days after transplantation
- Provided informed consent to participate
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
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Trial Site Locations
Total: 1 location
1
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Bologna, BO, Italy, 40138
Actively Recruiting
Research Team
G
Gaetano La Manna, MD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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