Actively Recruiting

Phase 1
Age: 18Years +
All Genders
NCT06819293

IB-T101 Injection for Treatment of Patients With Advanced Clear Cell Renal Cell Carcinoma

Led by Grit Biotechnology · Updated on 2026-04-14

12

Participants Needed

1

Research Sites

156 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is an open label, single center, dose escalation, and dose extension IIT study aimed at evaluating the safety, efficacy, and pharmacokinetics of IB-T101 in adult patients with advanced clear renal cell carcinoma

CONDITIONS

Official Title

IB-T101 Injection for Treatment of Patients With Advanced Clear Cell Renal Cell Carcinoma

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Voluntarily join the study, signed informed consent form, willing and able to comply with the study protocol
  • Age 18 years or older
  • Eastern Cooperative Oncology Group (ECOG) performance status score of 0 or 1
  • Expected survival time of at least 3 months
Not Eligible

You will not qualify if you...

  • Central nervous system dysfunction with clinical significance such as seizures, cerebral ischemia/hemorrhage, dementia, cerebellar diseases, cerebral edema, reversible posterior encephalopathy syndrome, or any autoimmune disease involving the CNS
  • Any form of primary or acquired immunodeficiency, including known HIV positive status
  • Experienced myocardial infarction or unstable angina within 6 months prior to screening
  • Pleural effusion requiring drainage for symptom management within 28 days prior to screening

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Tongji hospital, Huazhong University of Science and Technology

Wuhan, Hubei, China

Actively Recruiting

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Research Team

B

Bo Liu

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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