Identifying Asymptomatic Adults at Very High Cardiovascular Risk Using Carotid and Coronary Imaging Compared to European SCORE 2 Risk Calculation

What this Trial Is About

Researchers are investigating how to better identify people without symptoms who may be at very high risk for heart attacks due to the buildup of fatty plaques in arteries, known as atheroma. The study focuses on adults aged 40 to 80 and evaluates a strategy that uses imaging of carotid and coronary arteries compared to using the European SCORE2 risk calculator alone. This approach aims to improve early detection and prevention of cardiovascular events by finding plaques before symptoms appear. The study collects data from routine care in a national, single-center design without intervening treatments. Participants have their coronary artery reserve and endothelial function tested during a day hospital visit. The main tool compared is the SCORE2 algorithm, which estimates the 10-year risk of fatal or non-fatal heart attacks and strokes based on clinical factors. Imaging results are used to reclassify patients cardiovascular risk levels. Participants will be monitored to see if they are classified as very high cardiovascular risk within 12 months based on plaque detection and risk scores. The study involves reviewing clinical data and test results from cardiology consultations. The goal is to better understand how adding artery imaging can improve risk prediction beyond traditional methods and support more targeted prevention strategies for heart disease.

Identification of Asymptomatic Patients at Very High Cardiovascular Risk: Contribution of a Strategy Based on Carotid and Coronary Explorations, Compared to Simple Risk Calculation Using the European "SCORE 2" Algorithm. (IDEA-CVR)