Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06964282

Iliopsoas (IPB) and Pericapsular Nerve Group (PENG) Blocks Comparison on Analgesia and Recovery After Total Hip Arthroplasty

Led by University of Liege · Updated on 2026-05-06

118

Participants Needed

1

Research Sites

53 weeks

Total Duration

On this page

Sponsors

U

University of Liege

Lead Sponsor

C

Centre Hospitalier Universitaire de Liege

Collaborating Sponsor

AI-Summary

What this Trial Is About

Background: In recent years, regional anesthesia has become more popular because it can reduce pain and the need for strong pain medications like morphine. For hip surgery, the PENG block is already known to be effective. A newer method, called the iliopsoas plane block (IPB), is very similar and has also shown good results in hip arthroscopy. However, these two techniques have never been directly compared in patients undergoing hip replacement surgery using the posterior approach. Goal: This study aims to see if the IPB is just as effective as the PENG block for controlling pain and helping patients recover well after hip replacement surgery. Method: 118 adult patients scheduled for hip replacement under spinal anesthesia will be randomly assigned to receive either: IPB: 7 ml of Ropivacaine 7.5 mg/ml PENG: 14 ml of Ropivacaine 3.75 mg/ml Both injections are given under ultrasound guidance 30 minutes before spinal anesthesia. Neither the patient, the surgeon, nor the data collector will know which technique was used. Post-Surgery Care: All patients will receive standard pain relief, including: Paracetamol every 6 hours Etoricoxib once a day Morphine via a patient-controlled pump for 48 hours Main Outcome Measured: The primary goal is to compare pain during movement 6 hours after surgery, using a pain scale from 0 (no pain) to 10 (worst pain). The study will consider the two blocks equivalent if the difference in average pain scores is less than 1 point. Other Outcomes: Total morphine used in 48 hours Pain scores at rest and during movement at various time points Walking ability (2- and 6-minute walk tests, and timed-up-and-go test) Quality of recovery (using the QoR-15 questionnaire) Side effects of morphine Patient satisfaction Length of hospital stay Safety: Both techniques are safe and already used in clinical practice. Ultrasound guidance minimizes risks like nerve injury, bleeding, or infection. Conclusion: If the IPB is shown to be as effective as the PENG block, both can be considered reliable options for pain control and early recovery after hip replacement surgery.

CONDITIONS

Official Title

Iliopsoas (IPB) and Pericapsular Nerve Group (PENG) Blocks Comparison on Analgesia and Recovery After Total Hip Arthroplasty

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patients older than 18 years
  • ASA physical status classification I to III
  • Scheduled for elective total hip arthroplasty via posterior approach under spinal anesthesia
Not Eligible

You will not qualify if you...

  • Pregnancy confirmed by beta-HCG test if applicable
  • Known peripheral neuropathy or major neurological disease
  • Chronic pain syndromes or long-term opioid use over 20 mg oral morphine equivalents per day
  • Severe liver or kidney insufficiency
  • Allergy to local anesthetics
  • Major blood clotting disorders
  • Vulnerable patients such as minors or legally protected individuals

AI-Screening

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Trial Site Locations

Total: 1 location

1

Liege University Hospital

Liège, Belgium, 4000

Actively Recruiting

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Research Team

M

Michele Carella, MD, PhD, ESRA-DRA

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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