Actively Recruiting
Effect of Anesthesia, Positive Pressure Ventilation, and Imaging Method on Echocardiographic Grading of Aortic Regurgitation in Cardiac Surgery Patients Observational Trial
Led by University of Liege · Updated on 2025-04-10
100
Participants Needed
1
Research Sites
4 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to evaluate how different imaging methods and anesthesia affect the assessment of aortic regurgitation severity. It focuses on patients with known aortic regurgitation who are scheduled for cardiac surgery requiring trans-esophageal echocardiography (TEE). The study compares the grading of aortic insufficiency between transthoracic echocardiography (TTE) before anesthesia and TEE after anesthesia induction. Participants will have a TTE performed immediately before general anesthesia induction, followed by a TEE after anesthesia begins and positive pressure ventilation is applied. The study observes changes in the severity grading of aortic regurgitation between these two imaging techniques and conditions during surgery. During the study, researchers will assess the agreement between the aortic regurgitation grades from the pre-operative TTE and intra-operative TEE, as well as between the pre-operative TTE and a repeated TTE immediately after anesthesia induction. The study involves routine imaging assessments around the time of surgery, and participants will be monitored from enrollment through these imaging procedures.
CONDITIONS
Brief Title
Impact of Anesthesia, Positive Pressure Ventilation and Modality of Imaging on the Echocardiographic Assessment of the Severity of Aortic Regurgitation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Known aortic regurgitation of any grade
- Scheduled for a cardiac surgery procedure during which a trans-esophageal echo is planned
You will not qualify if you...
- Non sinus rhythm
- Mitral regurgitation more than mild
- Pre-operative critical state (according to the definition of the EuroSCORE II)
- Presence of a prosthetic aortic valve
- Contra-indication to trans-esophageal echo
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Day of surgery
Participants undergo echocardiographic assessments before and during cardiac surgery to evaluate the severity of aortic regurgitation.
1 pre-operative and 1 intra-operative imaging visit
Duration - Up to surgery day
Participants are observed for outcomes related to cardiac surgery and imaging assessments.
Visits as part of routine care
Trial Site Locations
Total: 1 location
1
Centre Hospitalier Universitaire de Liège
Liège, Belgium, 4000
Actively Recruiting
Research Team
A
Alan Houven, MD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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