Study on How Chronic Cough Affects Daily Activities and Reaction to High-Intensity Exercise in Adults

What this Trial Is About

Chronic cough is a widespread and challenging condition that affects up to 10% of people worldwide, causing both physical and psychological symptoms such as fainting, chest pain, tiredness, depression, and anxiety. This condition often results in social isolation and can reduce an individuals confidence and ability to perform everyday tasks or maintain an active lifestyle. The study aims to understand how unexplained chronic cough affects daily physical activities and to compare activity levels between people with chronic cough and healthy individuals matched by age, gender, and body mass index. Additionally, the study will evaluate how a single session of high-intensity exercise impacts cough frequency and severity in the short term. This observational study will involve monitoring physical activity using a wearable accelerometer device called ActiGraph LEAP over one week to objectively measure participants activity status. Participants will include those diagnosed with chronic cough lasting more than 8 weeks, defined by the European Respiratory Society standards, and experiencing significant symptoms. The study does not involve intervention treatments but focuses on data collection and monitoring activity and cough responses to exercise. Participants will wear the accelerometer device to track their physical activity during usual daily living. The researchers will assess the impact of chronic cough on activity levels and observe changes in cough after acute high-intensity exercise. Study visits will include screening for eligibility, ensuring recent chest imaging shows no contributing abnormalities, and collecting relevant health history. The study is expected to continue until December 2026, with no treatments administered, focusing on understanding the conditions impact and responses.

Impact of Chronic Cough on Activities of Daily Living and Response to Acute High-intensity Exercise