Actively Recruiting
Effects of Emotional Reactivity on Decision-Making in Adolescents With Nonsuicidal Self-Injury
Led by University of Electronic Science and Technology of China · Updated on 2024-04-11
80
Participants Needed
1
Research Sites
52 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Nonsuicidal self-injury (NSSI) involves intentionally causing physical harm without suicidal intent, mainly among adolescents. This research focuses on how emotional reactions and reward-related decision-making affect social choices during unfair experiences in adolescents with NSSI compared to healthy peers. The study investigates specific brain response patterns called prediction errors (PEs) that influence punishment decisions in social interactions. The study observes two groups of adolescents aged 15 to 18, those with NSSI and healthy controls, without administering treatments. Researchers will measure reward, valence, and arousal prediction errors, each taking about 20 minutes, to understand how these brain signals predict punishment decisions. There are no interventions; this is an observational study assessing decision-making differences linked to emotional reactivity. Participants will undergo assessments lasting around 20 minutes per outcome to record brain responses related to prediction errors. The study monitors how these signals differ between groups in social decision-making contexts. The total participation time corresponds to these evaluations, focusing on emotional and reward-related brain activity during unfair social scenarios. The study is led by the University of Electronic Science and Technology of China and runs until July 2027.
CONDITIONS
Brief Title
Impact of Emotional Reactivity on Dysfunctional Decision-Making in NSSI Adolescents
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 15 to 18 years
- Right-handed
- Normal or corrected normal visual acuity
- Meet DSM-5 frequency criteria with at least 5 days of nonsuicidal self-injury behaviors in the past year
You will not qualify if you...
- Diagnosis of borderline personality disorder, major depressive disorder, or other psychiatric disorders
- High suicidal risk
- Recent use of medications affecting neural activity
- Received or receiving Dialectical Behavior Therapy or other emotional treatments within the past 6 months
- Contraindications to MRI scanning such as metal implants or claustrophobia
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Single session lasting about 20 minutes
Participants complete tasks measuring emotional reactivity and decision-making during approximately 20-minute sessions.
1 visit (in-person)
Duration - Up to 1 year
Participants are observed to assess behavioral patterns related to nonsuicidal self-injury over time.
Visits as scheduled for assessments
Trial Site Locations
Total: 1 location
1
Sichuan Provincial Center for Mental Health, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China
Chengdu, Sichuan, China
Actively Recruiting
Research Team
B
Benjamin Becker
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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