Actively Recruiting
Impact of Emotional Reactivity on Dysfunctional Decision-Making in NSSI Adolescents
Led by University of Electronic Science and Technology of China · Updated on 2024-04-11
80
Participants Needed
1
Research Sites
186 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Nonsuicidal self-injury (NSSI) is defined as direct, intentional physical injury without suicidal intention. Studies revealed that dysfunctional interpersonal relationships and reward-related decision-making may play crucial roles in this maladaptive behavior, especially in adolescents. These interpersonal decision contexts are characterized by constant updating of expectations of rewards and the actual received rewards as well as the associated emotional reactions. These processes have recently been computationally formalized as prediction errors (PE), specifically reward PEs, valence PEs, and arousal PEs (Heffner et al., 2021; Nat Hum Behav). In the current study, the investigators aim to investigate whether these PEs make discernible contributions to social decisions in the context of unfair experiences among adolescents with NSSI and matched healthy control adolescents (HC). Specifically the investigators hypothesized that: 1) reward and emotional PEs show significant predictions of punishment decisions in both groups, 2) however, compared to HC adolescents, the NSSI group will exhibit selective dysfunctions in emotional but not reward PEs leading to punish a norm proposer who provided unfair offers.
CONDITIONS
Official Title
Impact of Emotional Reactivity on Dysfunctional Decision-Making in NSSI Adolescents
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 15 to 18 years of age
- Right-handed
- Normal or corrected normal visual acuity
- Meet DSM-5 criteria with 5 or more days of nonsuicidal self-injury behaviors in the past year
You will not qualify if you...
- Diagnosis of borderline personality disorder, major depressive disorder, or other psychiatric disorders
- High suicidal risk
- Recent use of medications that affect neural activity
- Received or currently receiving Dialectical Behavior Therapy or other treatments for emotional problems within the past 6 months
- Contraindication to MRI scanning such as metal implants or claustrophobia
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Sichuan Provincial Center for Mental Health, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China
Chengdu, Sichuan, China
Actively Recruiting
Research Team
B
Benjamin Becker
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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