Actively Recruiting

Age: 15Years - 18Years
All Genders
Healthy Volunteers
NCT05981677

Social Feedback and Dysfunctional Risk Taking in NSSI Adolescents

Led by University of Electronic Science and Technology of China · Updated on 2024-04-11

80

Participants Needed

1

Research Sites

186 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Nonsuicidal self-injury (NSSI) is defined as direct, intentional physical injury without suicidal intention. Problematic interpersonal relationships and decision-making have been demonstrated to play crucial roles in this maladaptive behavior, especially for adolescents. Accumulating evidence suggests that decision processes and risk-taking are strongly influenced by the affective state of the individual. However, whether these interactions are disrupted in NSSI adolescents has not been systematically examined. In the current study, the investigators modified one of the most widely used paradigms for measuring an individual's risk decision-making, the Balloon Analogue Risk Task (BART). The investigators combine social reward (green balloon), punishment (red balloon), and control feedback (yellow balloon), to investigate whether the NSSI adolescents have dysfunctional risk-taking behavior while facing different social outcomes. The investigators recruit one group of NSSI adolescents (n = 40) and one health control (HC) group (n = 40), to compare their risk-related decisions during the emotional BART. The investigators hypothesize that compared to HC, NSSI adolescents will show altered effects of social reward and punishment on risk-related decision-making, in particular higher risk avoidance in the context of social punishment.

CONDITIONS

Official Title

Social Feedback and Dysfunctional Risk Taking in NSSI Adolescents

Who Can Participate

Age: 15Years - 18Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Ages 15 to 18 years
  • Right-handed
  • Normal or corrected normal vision
  • Meet DSM-5 criteria with at least 5 days of nonsuicidal self-injury behaviors in the past year
Not Eligible

You will not qualify if you...

  • Diagnosis of borderline personality disorder, major depressive disorder, or other psychiatric disorders
  • High suicidal risk
  • Recent use of medications affecting neural activity
  • Received or receiving Dialectical Behavior Therapy or other emotional treatments in the past 6 months
  • Contraindications to MRI scanning such as metal implants or claustrophobia

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Sichuan Provincial Center for Mental Health, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China

Chengdu, Sichuan, China

Actively Recruiting

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Research Team

B

Benjamin Becker

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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