Actively Recruiting
Altered Neural Activation Patterns During Emotion Regulation in Adolescents With Nonsuicidal Self-Injury Under Naturalistic Immersive Emotional Engagement
Led by University of Electronic Science and Technology of China · Updated on 2024-04-11
80
Participants Needed
1
Research Sites
52 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are investigating how adolescents with nonsuicidal self-injury (NSSI) regulate their emotions using a strategy called acceptance. This observational study compares adolescents with NSSI to healthy controls to understand differences in emotional experience and brain activity. The study focuses on naturalistic emotional contexts using immersive video clips and measures brain responses through functional magnetic resonance imaging (fMRI). Participants include two groups of adolescents aged 15 to 18 years: one group with NSSI and one healthy control group. Both groups receive brief training on an acceptance mindset as an emotion regulation strategy. The study uses immersive videos to evoke emotions while measuring brain activity and subjective feelings. During the study, participants will report their emotional experiences and undergo about 30 minutes of fMRI scanning to record brain activity related to emotion regulation. Researchers will compare behavioral and neural responses between groups to better understand emotional regulation in NSSI. The total study duration and follow-up details are not specified.
CONDITIONS
Brief Title
Emotion Regulation Dysfunctions in NSSI Adolescents in Naturalistic Contexts
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 15 to 18 years
- Right-handed
- Normal or corrected normal visual acuity
- Meet DSM-5 frequency criteria for nonsuicidal self-injury (at least 5 days of NSSI behaviors in the past year)
You will not qualify if you...
- Diagnosis of borderline personality disorder, major depressive disorder, or other psychiatric disorders
- High suicidal risk
- Recent use of medications affecting neural activity
- Received or currently receiving Dialectical Behavior Therapy (DBT) or other emotional problem treatments within the past 6 months
- Contraindications to MRI (e.g., metal implants, claustrophobia, or other MRI unsuitability)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Single session
Participants receive brief training in acceptance versus emotional reactivity as an emotion regulation strategy.
1 visit (in-person)
Duration - Approximately 1 hour
Participants undergo assessments including self-report of negative subjective emotional experience and neural activity measurement via BOLD fMRI.
1 visit (in-person)
Trial Site Locations
Total: 1 location
1
Sichuan Provincial Center for Mental Health, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China
Chengdu, Sichuan, China
Actively Recruiting
Research Team
B
Benjamin Becker
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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