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ID07217756

Study on How Body Mass Index Affects Gum Health and Oral Conditions in Adolescents Wearing Braces

Led by University of Rochester · Updated on 2025-10-20

52

Participants Needed

1

Research Sites

N/A

Total Duration

AI-Summary

What this Trial Is About

Researchers are studying how increased body mass index BMI affects oral health and orthodontic treatment outcomes in adolescents aged 12 to 18 years undergoing fixed braces therapy. The study aims to determine if higher BMI is linked to greater gum inflammation, tooth discolorations, changes in tooth alignment, and elevated inflammatory and microbial markers in saliva and gum fluid. Two groups are compared one with increased BMI over 25.0 Kgm2 and a normal BMI group 18.5 to 24.99 Kgm2. Participants will be observed at two time points before braces are applied baseline and approximately six months later. During these visits, oral exams will assess gum health and tooth alignment, intraoral photos will be taken, and dental impressions will be made. Saliva and gum fluid samples will be collected to measure microbial counts and inflammatory markers. Additionally, participants will complete questionnaires about demographics, diet, and oral health quality of life. Throughout the study, researchers will measure changes in gum bleeding, white spot lesions on teeth, microbial levels of Candida albicans and Streptococcus mutans, as well as inflammatory markers and dietary habits. The study also tracks changes in body mass index and oral dryness. Safety and progression are monitored over the six-month period to understand the impact of BMI on oral health during orthodontic treatment.

CONDITIONS

Brief Title

Impact of Increased Body Mass Index on Adolescent Fixed Orthodontic Treatment. A Prospective Longitudinal Study

Research Team

D

Dimitrios Michelogiannakis, DDS, MS

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