Actively Recruiting
The Impact of Multiple Antihypertensive Therapy on Post-Induction Hypotension Burden in Cardiac Surgery Patients
Led by Konya City Hospital · Updated on 2026-05-06
160
Participants Needed
1
Research Sites
30 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study aims to investigate the impact of multiple preoperative antihyperstensive drug use on the burden of post-induction hypotension (PIH) in patients undergoing elective cardiac surgery. The researchers will observe whether the combination of different antihypertensive classes (such as ACE inhibitors, ARBs, beta-blockers, and calcium channel blockers) leads to a higher incidence and severity of blood pressure drops and increased need for vasoactive support during the period between anesthesia induction and surgical incision.
CONDITIONS
Official Title
The Impact of Multiple Antihypertensive Therapy on Post-Induction Hypotension Burden in Cardiac Surgery Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult patients aged 40 years and older
- Undergoing elective cardiac surgery such as isolated coronary artery bypass grafting, isolated valve surgery, or combined CABG and valve surgery via sternotomy
- Regularly taking at least one antihypertensive medication for 4 weeks or more before surgery
- Willing to participate and able to provide signed informed consent
You will not qualify if you...
- Emergency surgery
- Preoperative shock or need for high-dose inotropic or vasopressor drugs
- End-stage liver or kidney failure
- Uncontrolled hypertension
- Difficult intubation or prolonged anesthesia induction
- Ejection fraction below 35%
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
University of Health Sciences, Konya City Hospital
Konya, Turkey (Türkiye), 42080
Actively Recruiting
Research Team
M
Mustafa Aydemir, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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