Actively Recruiting
Comparison of Peripheral Nerve Quadruple Block Versus Adductor Canal Block Plus Surgical Infiltration for Pain Relief in Total Knee Arthroplasty
Led by GCS Ramsay Santé pour l'Enseignement et la Recherche · Updated on 2026-06-05
100
Participants Needed
2
Research Sites
4 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are comparing two pain relief methods for people undergoing total knee arthroplasty, commonly known as knee replacement surgery, due to gonarthrosis. The study evaluates whether a new quadruple peripheral nerve block provides better pain control than the current standard procedure, which combines an adductor canal block with surgical infiltration. The goal is to understand which approach improves patient recovery after surgery.
CONDITIONS
Brief Title
Infiltration or Nerve Blocks in Addition to Adductor Canal Block
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult male or female
- Patient with signed consent to participate in the study
- Patient with uni or bilateral primary gonarthrosis
- Indication for total knee arthroplasty
You will not qualify if you...
- History of knee fracture, arthroplasty, or osteotomy
- Known or unknown contraindication to locoregional analgesia or anesthesia products
- Neurological disease or stroke sequelae
- Mental deficiency or any condition hindering understanding or strict protocol adherence
- Not affiliated with the French social security system
- Under court protection, guardianship, or curatorship
- Pregnant or potentially pregnant women without effective contraception
- Already included in another therapeutic study protocol
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Day of surgery
Participants receive either a quadruple peripheral nerve block or an adductor canal block plus surgical infiltration as pain relief during total knee arthroplasty.
1 visit (in-person)
Duration - Up to 1 month after surgery
Participants are monitored and assessed for pain, recovery, knee function, and medication use up to 1 month after surgery.
Multiple visits at Hour 1, 2, 6, 12, 24, 48 and Month 1
Trial Site Locations
Total: 2 locations
1
Hôpital Privé Claude Galien
Quincy-sous-Sénart, France, 91480
Actively Recruiting
2
Clinique des Côtes du Rhône
Roussillon, France, 38150
Not Yet Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
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