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Led by GCS Ramsay Santé pour l'Enseignement et la Recherche · Updated on 2026-06-05
100
Participants Needed
2
Research Sites
4 weeks
Total Duration
Researchers are comparing two pain relief methods for people undergoing total knee arthroplasty, commonly known as knee replacement surgery, due to gonarthrosis. The study evaluates whether a new quadruple peripheral nerve block provides better pain control than the current standard procedure, which combines an adductor canal block with surgical infiltration. The goal is to understand which approach improves patient recovery after surgery.
CONDITIONS
Infiltration or Nerve Blocks in Addition to Adductor Canal Block
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GCS Ramsay Santé pour l'Enseignement et la Recherche
Lead Sponsor
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Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Day of surgery
Participants receive either a quadruple peripheral nerve block or an adductor canal block plus surgical infiltration as pain relief during total knee arthroplasty.
1 visit (in-person)
Duration - Up to 1 month after surgery
Participants are monitored and assessed for pain, recovery, knee function, and medication use up to 1 month after surgery.
Multiple visits at Hour 1, 2, 6, 12, 24, 48 and Month 1
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
Have more questions? Get in touch with our team for quick support
Yoann Elmaleh, Olivier Maupain, Karim Guessous...
https://pubmed.ncbi.nlm.nih.gov/42481203/GCS Ramsay Santé pour l'Enseignement et la Recherche
Lead Sponsor
