Completed
Influence of Diet and Endurance Running on Intramuscular Lipids Measured at 4.1 TESLA
Led by National Center for Research Resources (NCRR) · Updated on 2005-06-24
N/A
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this pilot investigation is to use 1 H Magnetic Resonance Spectroscopy (MRS) to 1) document the change in intra-muscular lipid stores (IML) before and after a prolonged bout of endurance running and, 2) determine the pattern (time course) of IML replenishment following an extremely low-fat diet (10% of energy from fat) and a moderate-fat diet (35% of energy from fat). Specifically, the study will evaluate the change in IML following a 2-hour training run and the recovery of IML in response to the post-exercise low-fat or moderate-fat diet in 10 endurance trained athletes who will consume both diets in a randomly assigned cross-over fashion. We hypothesize that IML will be depleted with prolonged endurance exercise, and that replenishment of IML will be impaired by an extremely low-fat diet compared to a moderate-fat diet. Results of this pilot study will be used to apply for extramural grant support from NIH or the US Armed Forces to investigate the effect of dietary fat on the health and performance of individuals performing heavy physical training. It is anticipated that this methodology could also be employed in obesity research to delineate, longitudinally, the reported cross-sectional relationships among IML stores, insulin resistance and obesity.
CONDITIONS
Brief Title
Influence of Diet and Endurance Running on Intramuscular Lipids Measured at 4.1 TESLA
Who Can Participate
Eligibility Criteria
You may qualify if you...
Inclusion Criteria:
- Healthy volunteers (developmental phase)
- Healthy endurance-trained subjects
- Maximum age for males is 39
- Maximum age for females is 49
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
Trial Site Locations
Total: 1 location
1
The University of Alabama at Birmingham Nutrition Sciences Department
Birmingham, Alabama, United States, 35294
Status Unknown
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
N/A
Model
N/A
Primary Purpose
TREATMENT
Number of Arms
0
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