Study of Early Healing Effects on One-Year Results of Regenerative Surgery for Advanced Periodontitis

What this Trial Is About

Researchers are studying patients with advanced Stage III-IV periodontitis to understand how early healing after periodontal regenerative surgery affects long-term treatment success. This observational study evaluates the relationship between wound healing quality at 1 and 2 weeks post-surgery and clinical and radiographic outcomes at 12 months. It also explores various patient, site, and surgical factors that may influence early healing. Participants undergo periodontal regenerative surgery involving surgical cleaning of deep bone defects followed by regenerative techniques that may include biologics, bone grafts, or blood clot alone. Various papilla preservation surgical methods are used during the procedure. All patients receive this surgery based on clinical need, and their early wound healing is assessed at 1 and 2 weeks to stratify outcomes. Throughout the study, participants have assessments including clinical attachment level, probing pocket depth, bleeding on probing, radiographic evaluations, and healing indices at baseline, 1 week, 2 weeks, and 12 months. Researchers also monitor pain medication use shortly after surgery. The total participation spans at least 12 months to capture the long-term effects of early healing on periodontal regeneration.

Influence of Early Wound Healing on the Outcomes of Regenerative Periodontal Surgery