Is Intraligamentary Injection the Anesthesia of Choice for Symptomatic Irreversible Pulpitis in Mandibular Molars? A Multicenter Randomized Comparative Trial.

What this Trial Is About

The trial investigates two methods of anesthesia for patients with symptomatic irreversible pulpitis in mandibular molars, a condition that makes pain control during dental treatment challenging. This randomized study aims to compare the effectiveness of intraligamentary injection and inferior alveolar nerve block in controlling pain during endodontic access. The research is conducted across multiple dental centers using standardized criteria and validated pain scales. Participants will be randomly assigned to receive either intraligamentary anesthesia with 2% lidocaine and epinephrine using a dental syringe or the conventional inferior alveolar nerve block with the same anesthetic solution. These procedures are administered before the dental access to evaluate which technique better eliminates pain. The study is single-blinded and includes follow-up measures at the end of treatment and seven days later. During the trial, pain will be assessed immediately after access cavity preparation. Additional measurements include the need for supplementary anesthesia during the procedure, patient satisfaction both immediately and at seven days post-treatment, and postoperative pain at seven days. Participants will be monitored through follow-up visits and data collection to evaluate the outcomes and safety of each anesthesia method. The total participation time includes the initial treatment and a one-week follow-up.

Intraligamentary vs Inferior Alveolar Nerve Block for Pulpitis: A Randomized Clinical Trial