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HIPAA Compliant
ISO 27001 Certified

Actively Recruiting

Phase Not Applicable
Age: 18Years - 75Years
FEMALE
ID07510269

Comparing Two Ultrasound-Guided Nerve Blocks for Pain Relief After Mastectomy in Women Aged 18 to 75

Led by Uludag University · Updated on 2026-04-03

66

Participants Needed

1

Research Sites

4 weeks

Total Duration

AI-Summary

What this Trial Is About

Postoperative pain after mastectomy surgery is a common issue that can reduce patient comfort, delay recovery, and extend hospital stays. This research compares two ultrasound-guided regional anesthesia techniques, the serratus anterior plane SAP block and the serratus posterior superior intercostal plane SPSIP block, to evaluate their effectiveness in managing pain in female patients aged 18 to 75 years undergoing elective mastectomy. The study focuses on identifying which technique better improves pain control and recovery outcomes. Participants will be randomly assigned to receive either the SAP block or the SPSIP block before surgery. The SAP block involves injecting 30 mL of 0.25% bupivacaine between the serratus anterior muscle and rib surface, while the SPSIP block delivers the same dose between the serratus posterior superior and intercostal muscles. All patients receive standardized general anesthesia and perioperative care, including medications like midazolam, fentanyl, and desflurane. Monitoring during surgery records vital signs and opioid use. After surgery, pain levels are measured using a Numeric Rating Scale at multiple time points up to 48 hours. Researchers also track the time until the first pain medication is needed, total analgesic use, complications, and satisfaction scores from patients and surgeons. Hemodynamic data during surgery and opioid consumption are recorded. This detailed follow-up helps assess differences in pain relief and recovery between the two anesthesia methods.

CONDITIONS

Brief Title

Investigation of the Effects of Serratus Posterior Superior Intercostal Plane Block and Serratus Anterior Plane Block on Perioperative Analgesia Management in Patients Scheduled for Mastectomy

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