Actively Recruiting

Phase Not Applicable
Age: 18Years - 60Years
All Genders
Healthy Volunteers
NCT06081946

Investigation of the Effects of Sleep Fragmentation on Itch and Pain Sensitivity

Led by Aalborg University · Updated on 2024-11-22

30

Participants Needed

1

Research Sites

158 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

In This experiment, the investigators would like to test following hypotheses regarding the influence of sleep fragmentation on itch: * To investigate similarity and differences between itch and pain by comparing the effect of sleep deprivation in them. * To evaluate the inflammatory state induced by sleep fragmentation via the analysis of C-reactive protein (CRP) levels from blood samples. * To correlate the anxiety and depression scores (evaluated through questionnaires) with itch and pain sensitivity and evaluate how they are affected by sleep fragmentation.

CONDITIONS

Official Title

Investigation of the Effects of Sleep Fragmentation on Itch and Pain Sensitivity

Who Can Participate

Age: 18Years - 60Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Healthy men and women
  • Aged 18 to 60 years
  • Speak and understand English
  • Access to a smartphone during the experimental nights
Not Eligible

You will not qualify if you...

  • Pregnancy or lactation
  • Drug addiction including cannabis, opioids, or other drugs
  • History of neurological, dermatological, immunological, musculoskeletal, cardiac, or mental illnesses affecting results (e.g., neuropathy, muscular pain, anxiety, depression, schizophrenia)
  • Moles, wounds, scars, or tattoos in the treatment or test areas
  • Current use of medications like antihistamines or painkillers that may affect the trial
  • Skin diseases
  • Alcohol or painkiller use within 24 hours before and during study days
  • Acute or chronic pain and itch
  • Participation in other trials within 1 week before study entry (4 weeks for pharmaceutical studies)
  • Lack of ability to cooperate

AI-Screening

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Trial Site Locations

Total: 1 location

1

Aalborg University

Aalborg, Denmark, 9620

Actively Recruiting

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Research Team

S

Silvia Kjær-Staal Lo Vecchio

CONTACT

S

Silvia Lo Vecchio

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

BASIC_SCIENCE

Number of Arms

1

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