Actively Recruiting
Prophylactic Oral Iron Supplementation for the Prevention of Iron Deficiency Anemia After Sleeve Gastrectomy A Prospective Comparative Cohort Study
Led by Cairo University · Updated on 2026-02-11
66
Participants Needed
1
Research Sites
26 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating whether taking extra iron pills after laparoscopic sleeve gastrectomy (LSG) surgery can better prevent iron deficiency anemia (IDA) compared to taking only a standard multivitamin. This observational study focuses on adults aged 18 to 65 undergoing primary LSG, aiming to fill the evidence gap about the best way to manage iron levels after surgery. IDA is a common long-term issue after this weight loss surgery, affecting quality of life and health outcomes. Participants are grouped based on their hospital unit's usual care: one group takes a daily prophylactic iron supplement (Ferrodep®, 60 mg elemental iron per day, given as two 30 mg capsules 12 hours apart) plus a standard multivitamin, while the other group takes only a standard multivitamin containing about 10 mg of iron (Centrum Silver®) with no added iron. The study observes these two approaches without assigning treatments, reflecting real-world care practices. Participants will have blood tests before surgery and at 3 and 6 months afterward to measure iron levels, anemia status, and other blood markers. Researchers will also collect information on supplement adherence and patient-reported fatigue, along with reviewing medical records. The main outcome is the rate of IDA at 6 months post-surgery. Follow-up visits will include health and quality of life assessments, with a total study duration of 6 months after surgery for each participant.
CONDITIONS
Brief Title
Iron Supplementation and Anemia After Sleeve Gastrectomy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 to 65 years scheduled to undergo primary laparoscopic sleeve gastrectomy (LSG)
- Able to understand and provide written informed consent
- Willing and able to attend follow-up visits for 6 months after surgery
You will not qualify if you...
- History of major gastrointestinal surgery such as bowel resection or gastrectomy
- Existing malabsorptive conditions like inflammatory bowel disease or celiac disease
- Diagnosed with other forms of anemia that affect iron deficiency anemia diagnosis, including thalassemia or vitamin B12/folate deficiency
- Any condition that may interfere with participation or pose significant risk as judged by the investigator
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Day of surgery
Participants undergo laparoscopic sleeve gastrectomy surgery and begin their assigned post-operative supplementation according to the standard care protocol of their surgical unit.
1 visit (in-person)
Duration - 6 months
Participants are monitored for iron deficiency anemia and other outcomes, with assessments including laboratory tests and patient-reported outcome measures.
3 visits (baseline pre-operative, 3 months post-operative, and 6 months post-operative; in-person)
Trial Site Locations
Total: 1 location
1
Faculty of Medicine Cairo University
Cairo, Al-Manial Cairo, Egypt
Actively Recruiting
Research Team
A
Ahmed Eid Aziz, Lecturer
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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