Study of Ketorolac for Pain Relief During Lower Limb Orthopedic Surgeries Using Spinal Anesthesia and Tourniquet

What this Trial Is About

Researchers are evaluating the use of intravenous ketorolac as a regional analgesic during lower limb orthopedic surgeries performed with a tourniquet and spinal anesthesia. The study aims to compare the effects of ketorolac injected directly into the isolated limb versus ketorolac given intravenously before tourniquet inflation, focusing on how long the postoperative pain relief lasts. Participants will be randomly assigned to one of two groups one receiving ketorolac injected into the isolated limb after tourniquet inflation and a saline injection into the general circulation, and the other receiving saline in the isolated limb with ketorolac given intravenously before tourniquet pressure. All patients will also receive standard spinal anesthesia and postoperative pain medications such as paracetamol and diclofenac. During the study, participants will be monitored for pain levels at rest and during movement at several time points within 24 hours after surgery. Researchers will also record the total amount of pain medication used, as well as how quickly sensory and motor function recover from spinal anesthesia. The primary outcome is the duration of pain relief after surgery, with safety and recovery closely observed throughout the postoperative period.

Ketorolac Intravenous Regional Analgesia in Lower Limb Surgeries