Actively Recruiting
Effects of Pericapsular Nerve Group Block on Postoperative Recovery for Total Hip Arthroplasty
Led by Umraniye Education and Research Hospital · Updated on 2025-11-19
60
Participants Needed
1
Research Sites
63 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating the effects of the Pericapsular Nerve Group (PENG) block on patients undergoing Total Hip Arthroplasty (THA) surgery with spinal anesthesia. The study aims to determine whether the PENG block reduces postoperative pain scores, lowers the need for opioid painkillers, and enables earlier mobilization compared to not using the block. It also investigates the impact of the block on hip joint function, length of hospital stay, perioperative blood pressure and heart rate, and any side effects after surgery. In this randomized controlled trial, 60 patients aged 40 to 85 years undergoing THA surgery were divided into two groups: one received the PENG block before surgery, where 20 ml of 0.5% bupivacaine was injected between specific tissues using ultrasound guidance, and the other group did not receive the block. Both groups had spinal anesthesia. Additionally, all patients received multimodal pain control, including local infiltration of bupivacaine and lidocaine at the surgical site, and postoperative pain management with tramadol via a patient-controlled analgesia device plus intravenous paracetamol. Participants are monitored for postoperative pain at multiple time points up to 48 hours after surgery, time taken to begin moving after surgery, hip joint openness at 24 hours, and total opioid use in 48 hours. Side effects related to the PENG block and perioperative blood pressure and heart rate at specific times are also recorded. The study tracks the length of hospital stay. This structured approach helps researchers assess recovery quality and safety during the early postoperative period.
CONDITIONS
Brief Title
Effects of Pericapsular Nerve Group Block on Postoperative Recovery for Total Hip Arthroplasty
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Undergoing Total Hip Arthroplasty performed by the posterior approach
- Age between 40 and 85 years
- American Society of Anesthesiologists (ASA) physical status classification of 1 to 3
You will not qualify if you...
- Age under 40 or over 85 years
- ASA physical status classification of 4 or higher
- Cognitive impairments such as Alzheimer's disease, dementia, or delirium
- Hip fracture
- Infection at the block application site
- Allergy to local anesthetic agents
- Patients who do not consent to participate
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Day of surgery and the initial 48 hours postoperatively
Participants receive spinal anesthesia followed by either a Pericapsular Nerve Group (PENG) block or no block before undergoing total hip arthroplasty surgery. Multimodal pain management is provided post-surgery.
1 surgery day visit and multiple assessments over 48 hours postoperatively
Duration - Up to hospital discharge, typically within days after surgery
Participants are monitored for postoperative pain, opioid use, hip joint function, side effects, and length of hospital stay after surgery.
Daily visits or assessments until discharge
Trial Site Locations
Total: 1 location
1
UmraniyeERH
Istanbul, Umraniye, Turkey (Türkiye), 34734
Actively Recruiting
Research Team
Z
zeliha tuncel, ass prof
H
hale arkan tuna, specialist dr
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here