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Study of Knee Osteoarthritis and Long-Term Outcomes After Tibial Plateau Fractures in Norrbotten, Sweden
Led by Umeå University · Updated on 2024-06-18
500
Participants Needed
1
Research Sites
N/A
Total Duration
AI-Summary
What this Trial Is About
Researchers are studying knee osteoarthritis in patients from the Swedish region of Norrbotten who experienced tibial plateau fractures between 2001 and 2015. The study aims to find out how common radiographic knee osteoarthritis is after these fractures and to understand medium and long-term functional outcomes. It also looks for risk factors linked to these outcomes, including gender, age, body mass index, fracture pattern, and treatment method. Participants in this observational study undergo radiographic evaluations, clinical examinations, and assessments using the Knee injury and Osteoarthritis Outcome Score KOOS. General health and quality of life are measured with the EuroQol 5-Dimension 5-level EQ-5D-5L tool. Data from the Swedish Fracture Register and the Swedish Arthroplasty Register are used to follow long-term results and outcomes. During the study, participants will be monitored for at least five years after their injury to track the development of osteoarthritis through imaging and condition-specific scores. Researchers will assess symptoms, knee function, and health-related quality of life over time. The primary outcome is the number of participants showing radiographic osteoarthritis at five years or more. Secondary outcomes include symptom and function scores, condition-specific quality of life, and general health quality of life evaluations.
CONDITIONS
Brief Title
Knee Osteoarthritis in the Region of Norrbotten
Research Team
P
Przemyslaw T Paradowski, MD, PhD
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