Actively Recruiting
L-serine and Strength Training in the Elderly
Led by University of Vienna · Updated on 2026-03-12
126
Participants Needed
1
Research Sites
143 weeks
Total Duration
On this page
Sponsors
U
University of Vienna
Lead Sponsor
M
Medical University of Vienna
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study investigates whether taking the amino acid L-serine, either alone or in combination with targeted strength training, can have a positive effect on mental performance, brain function, and physical fitness in older people. Healthy, independent women and men aged 65 to 85 are eligible to participate. Participants will be randomly assigned to one of three groups: placebo, L-serine, or L-serine combined with strength training. Cognitive tests, physical performance tests, and blood and brain tests will be conducted over a period of 48 weeks. The aim is to gain a better understanding of how nutrition and exercise can contribute to healthy aging.
CONDITIONS
Official Title
L-serine and Strength Training in the Elderly
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Men and women between the ages of 65 and 85
- Mini-Mental-State score greater than 23
- Independently mobile without walking aids such as a walker or cane
You will not qualify if you...
- Chronic diseases that prevent medical training therapy
- Regular strength training more than once a week in the last 6 months
- Frailty Index of 3 or higher
- No written consent for physical performance testing
- Regular use of cortisone-containing medications or antibiotics
- Claustrophobia or metal/ magnetic materials in or on the body preventing MRI
- Less than 70% adherence to planned L-serine intake or strength training
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
NuTraLab
Vienna, State of Vienna, Austria, 1070
Actively Recruiting
Research Team
K
Karl-Heinz Wagner, Prof.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
3
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