Study of 810 nm Light Therapy to Reduce Knee Pain and Synovitis in Adults Aged 40 to 80

What this Trial Is About

Knee pain is a common issue among middle-aged and older adults, often linked to synovitis, a condition present in up to 80% of those with moderate knee pain. Researchers are evaluating whether 810 nm light therapy can reduce knee pain and synovitis in people with chronic knee pain. This randomized, placebo-controlled trial aims to build on prior animal studies that showed this specific light wavelength helped reduce inflammation and pain-like symptoms. The trial involves 90 participants with chronic knee pain and ultrasound-confirmed synovitis. They will be randomly assigned to receive either 810 nm light therapy or a sham placebo therapy using a wearable device. Treatments are given twice weekly for five weeks. The study compares knee pain using the Visual Analogue Scale and synovitis assessed by ultrasound. Secondary measures include knee function tests and walking speed. Assessments occur at baseline, after treatment at week 5, and at 1 month and 6 months post-treatment. During the study, participants will have regular evaluations including pain scales, ultrasound scans, physical function tests, and questionnaires. Researchers will monitor adverse events throughout the treatment and follow-up periods. Outcomes focus on changes in knee pain and synovitis over time to assess the therapys effects. The total participation includes the 5-week treatment plus 6 months of follow-up to track lasting effects and safety.

Light Therapy on Pain and Synovitis