LiPO Teen: Follow-up Study of Lifestyle in Pregnancy Intervention to Identify Modifiable Risk Factors for Childhood Obesity

What this Trial Is About

Researchers are conducting a follow-up study of the Lifestyle in Pregnancy (LiP) randomized controlled trial from 2007-2010. The original trial included 360 pregnant women with a body mass index of 30 or higher, who were assigned to either a low-calorie diet and physical activity intervention or standard care. This follow-up, called LiPO Teen, aims to understand if lifestyle changes during pregnancy can prevent obesity and related health issues in both the mothers and their 14-year-old children. Participants are divided into two groups based on the original trial: those who received lifestyle advice on diet and physical activity, and those who received no intervention. The follow-up involves inviting mother-child pairs who completed the initial study to a 2-hour clinical examination 14 years after the pregnancy intervention to evaluate long-term effects. During the examination, researchers will assess fat mass index using DEXA scans and collect data on many health indicators such as glycemic variability, mental health, diet, physical activity, puberty stage, blood pressure, and various metabolic and inflammatory markers. This comprehensive evaluation aims to identify modifiable risk factors for childhood obesity. The total data collection period for outcomes is two years, and the study is sponsored by Odense University Hospital.

LiPO Teen (the Lifestyle in Pregnancy and Offspring Teenagers