Adiyaman Merkez

Researchers are investigating the use of Gram staining of the first urine collected after kidney puncture during percutaneous nephrolithotomy PCNL to predict systemic inflammatory responses in patients undergoing this procedure. The study compares patients receiving an expanded empirical antibiotic regimen based on the Gram stain results to those whose antibiotic treatment is adjusted later according to symptoms and culture outcomes. The goal is to evaluate the diagnostic value of Gram stain in anticipating and preventing post-surgical complications. Participants are randomly assigned to one of two groups the experimental group receives antibiotic treatment guided by Gram staining of the first urine after the renal puncture, while the control group undergoes PCNL without this intervention, relying on standard care and symptom-based antibiotic adjustments. This is a prospective, randomized controlled study with triple masking to reduce bias. During the study, researchers will assess the effectiveness of Gram stain in predicting systemic inflammatory responses immediately after surgery and monitor changes in antibiotic regimens based on bacterial findings. Patients will be observed for signs of inflammation and infection, with data collected promptly post-operation to evaluate the impact of the diagnostic approach on clinical outcomes and antibiotic use.

Researchers are studying the effect of a behavioral homework program on stone clearance rates after retrograde intrarenal surgery RIRS, a procedure used to treat kidney stones. This study aims to see if instructing patients to perform percussion tapping and movement or position changes at home can help stones pass more easily. The study is randomized and evaluates these home-based behavioral interventions compared to standard care without such homework. Participants are assigned to one of two groups one group receives instructions for percussion and position changes to do at home after their RIRS procedure, while the other group receives standard RIRS without additional intervention. The study focuses on evaluating stone clearance and the need for further surgery or complications one month after the procedure. During the study, participants will be monitored for stone-free rates one month after surgery, along with any complications or secondary surgeries required. Researchers will track these outcomes to assess the effectiveness of the home-based behavioral approach. The study is sponsored by Adiyaman University and plans to enroll adults aged 18 and older undergoing RIRS.

This clinical trial studies patients with gingival recession classified as Cairo RT1 equivalent to Miller Class I or II who also have non-carious cervical lesions or existing cervical restorations. The research aims to evaluate how different restorative materials used in Class V cervical lesions affect the results of root coverage surgery performed with a subepithelial connective tissue graft. The goal is to identify which restorative approach leads to better clinical outcomes in terms of root coverage and soft tissue stability. Participants are randomly assigned to one of three groups no restoration, restoration with glass ionomer cement, or restoration with resin composite before undergoing root coverage surgery. All patients receive standardized periodontal treatment before surgery. The study compares these restorative approaches to see their influence on the success of the root coverage procedure. During the study, participants will have clinical evaluations including measurements of root coverage percentage and soft tissue healing at baseline and follow-up visits up to six months post-surgery. Researchers will also assess gingival recession depth, clinical attachment level, keratinized tissue width, probing depth, dentin hypersensitivity, and esthetic results. The study monitors the stability of treated sites and participant compliance throughout the trial period.

Researchers are investigating how self-efficacy, or a persons confidence in managing their health, relates to medication adherence in individuals with coronary artery disease CAD. This descriptive and correlational study focuses on patients diagnosed with CAD for at least one year, aiming to understand how belief in managing chronic disease influences their treatment adherence. The study will be conducted between March and October 2025 at Adyaman University Training and Research Hospital with a planned sample size of 135 participants. The study is observational and does not involve any interventions or experimental treatments. Data will be gathered through self-administered questionnaires including the Descriptive Information Form, the 6-Item Self-Efficacy for Managing Chronic Disease Scale, and the Medication Adherence Report Scale MARS. Participants are those diagnosed with CAD such as angina pectoris or myocardial infarction, who can communicate in Turkish and have no mental disorders. Participants will complete questionnaires to report their self-efficacy and medication adherence during the study period. Researchers will assess self-efficacy scores and medication adherence scores collected between March and October 2025. The findings aim to help healthcare professionals, especially nurses, develop better education and counseling strategies to support CAD patients in managing their condition effectively.

Researchers are evaluating how using technological devices like videos or games during circumcision affects pain and anxiety levels in boys aged 6 to 18 undergoing the procedure. The study aims to compare children who watch videos or play games during circumcision with those who do not receive any visual or verbal stimulation. This research is sponsored by Adiyaman University and focuses on the immediate impact on anxiety and worry during the procedure. Children in the study are randomly assigned to one of two groups one group will undergo circumcision while watching videos or playing games, and the other group will have the procedure without any visual or verbal stimulation. The circumcision is performed with local anesthesia. The study starts with hospitalization and continues through to a follow-up check-up after discharge. Participants will be assessed for changes in anxiety and worry immediately after the procedure, both in the children and their parents. The research team will monitor these emotional responses to understand the effect of the technological intervention. The total participation includes the procedure day and a follow-up appointment after the child is discharged from the hospital.

Researchers are evaluating how a three-dimensional 3D imaging technique affects the learning process for percutaneous nephrolithotomy PCNL during specialist training. This study focuses on patients with kidney stones larger than 2 cm who require PCNL, aiming to understand if 3D imaging helps improve surgical outcomes compared to standard PCNL methods. Participants will be randomly assigned to either receive PCNL using the 3D imaging technique or standard PCNL without this imaging. The 3D imaging technique helps surgeons plan the best access route to the kidney stone by providing a detailed virtual reconstruction, which may reduce the learning curve for new surgeons. The study is double-blinded to reduce bias and compares outcomes immediately after surgery and one month later. During the study, researchers will monitor several important outcomes including the number of participants experiencing bleeding or complications during or immediately after surgery, how many are stone-free one month post-surgery, and the length of hospital stay after the procedure. The study involves regular assessments and follow-ups to track these outcomes, with all care and evaluations provided as part of the trial period ending in October 2025.

Foreign body obstruction is a common emergency, especially in children, and can be life-threatening without timely treatment. This research evaluates how hands-on Heimlich maneuver training for mothers of children with disabilities affects their knowledge, skills, confidence, and anxiety. The study is a randomized controlled trial including 70 mothers of children aged 1 to 8 years attending a rehabilitation center. Mothers in the experimental group receive individual training combining theoretical instruction and practical demonstrations with a pediatric Heimlich mannequin. Each mother practices the maneuver until performed correctly, with sessions lasting 30 to 45 minutes. They also receive a visual guide on their cell phones. The control group does not receive training during the study but will be offered the same training after post-test evaluations. Pre- and post-tests assess knowledge and skills one month apart. Participants complete questionnaires measuring their knowledge of the Heimlich maneuver, self-efficacy, and anxiety levels at baseline, 4 weeks, and 8 weeks. Data collection involves demographic forms and skill tests. Mothers in the control group take pre- and post-tests without training initially. After the study, all mothers receive the training. The study monitors changes within and between groups to understand the trainings impact on mothers caring for children with disabilities.