Kastamonu Merkez

This research aims to evaluate whether breathing exercises help reduce lung complications in patients with rib fractures. The study focuses on adults aged 18 to 100 who have suffered isolated chest injuries within 24 hours. Researchers want to compare lung function and the occurrence of pulmonary problems like pneumonia between two groups receiving different treatments. Participants will be randomly divided into two groups. One group will receive standard pain relief treatment using paracetamol and dexketoprofen. The other group will receive the same pain relief plus respiratory physiotherapy with a triflow device, performing breathing exercises for 8 hours a day, 10 times per hour. This approach aims to improve lung expansion and prevent complications. During the study, lung function tests measuring FEV1, FVC, and FEV1FVC ratios will be done on days 2 and 7. Researchers will also monitor the number of participants developing pneumonia within 7 days. The trial lasts for one week, focusing on lung performance and safety. Participants pain scores and respiratory capacity will be tracked to assess the effects of the breathing exercises compared to routine treatment.

Researchers are evaluating a novel rapid diagnostic device designed to detect Crimean-Congo Hemorrhagic Fever CCHF at the point of care in secondary health care clinics in Turkey. This study aims to determine the sensitivity and specificity of the test using samples of whole blood, serum, and capillary blood from adults suspected of CCHF infection. The goal is to meet or exceed the World Health Organizations minimum sensitivity of 90% and specificity of 80% for this condition. The study involves using a rapid diagnostic test RDT developed by the Liverpool School of Tropical Medicine and Global Access Diagnostics. This device detects CCHF viral antigens quicklyproviding results within 20 minutesand is simpler and more affordable than the standard RT-PCR test. Participants suspected of infection will have blood drawn and tested with the RDT at four endemic secondary health care sites in Turkey. Participants will provide blood samples which will be compared against PCR testing to evaluate the accuracy of the new device. The study will also collect questionnaires from end users to assess usability. Researchers will measure diagnostic sensitivity, specificity, predictive values, test accuracy, and the time taken to obtain results. The study includes follow-up until all diagnostic results and questionnaires are received, which may take up to a month after the last participant is recruited.

The trial investigates the effects of two therapies, Modified Constraint-Induced Movement Therapy mCIMT and Mirror Therapy MT, on improving upper limb motor function, activity participation, and independence in daily living for adults with hemiplegic stroke. Stroke often causes upper extremity impairment that limits daily activities and social engagement. This research compares these two neuroplasticity-based treatments to determine which better supports functional recovery and quality of life. Participants will be randomly assigned to one of two groups those receiving mCIMT, which involves restricting movement of the unaffected arm and intensive training of the affected limb, and those receiving MT, where they perform tasks while watching the unaffected arms reflection to create an illusion of movement. Both interventions are delivered face-to-face in a rehabilitation setting over a 4-week period, alongside routine rehabilitation care. Participants will undergo assessments before and after treatment by a blinded evaluator using standardized tools measuring upper limb motor function, independence in daily activities, and participation levels. Follow-up includes evaluations of motor recovery and daily function at baseline and after the 4-week therapy. The study aims to provide clear comparisons of these therapies impact on stroke recovery over this time frame.

This research aims to support mothers caring for children with moderate to severe mental disabilities, including conditions such as hearing, visual, physical disabilities, autism spectrum disorder, and emotional or behavioral disorders. The study evaluates artistic activities designed to reduce the mental burden and improve the psychological well-being of these caregivers. It uses a quasi-experimental pre-test and post-test design to assess the impact of these activities over time. Participants will be involved in various art therapy sessions such as wood painting, lithography, jewelry design, mud free shaping, and expression workshops. These artistic and training activities will be carried out over a total of 12 weeks. Before and after this period, psychological well-being and caregiver burden will be assessed using several validated scales and questionnaires. Mothers will complete questionnaires covering descriptive characteristics and psychological well-being, including the Psychological Well-being Scales, Caregiver Burden Scale, Emotion Expression Scale, and Stress Coping Styles Scale. Data analysis will determine changes in mental well-being and caregiver burden before and after the intervention. The studys primary outcome is to increase mental well-being, measured seven weeks after starting the activities, with monitoring conducted throughout the 12-week program.

The trial investigates how laughter yoga and pilates affect pregnancy adjustment, anxiety, and prenatal attachment in pregnant women who have received childbirth preparation training. It focuses on pregnant women beyond 20 weeks without multiple or risky pregnancies, exploring ways to support their emotional and physical well-being during this important life phase. The study is sponsored by Istanbul University - Cerrahpasa and aims to better understand complementary methods to manage stress and promote positive pregnancy experiences. Participants are randomly assigned to one of three groups laughter yoga, pilates, or education only. The laughter yoga group practices sessions twice a week for four weeks, each lasting 45 minutes, combining laughter exercises and yoga breathing techniques in groups up to 15 people. The pilates group also meets twice weekly for four weeks, with sessions focusing on pregnancy-safe pilates exercises lasting 45 minutes and groups up to 10 people. The education group attends routine pregnancy school trainings covering topics like postpartum care and breastfeeding. Each group completes a pre-test in the first week and a final test after four weeks. During the study, pregnant women participate in assessments measuring pregnancy-related anxiety, pregnancy adjustment, and prenatal attachment using standardized scales at the four-week mark. Routine pregnancy school training is provided by midwife trainers for all groups. The researchers monitor participants progress through these tests to evaluate the impact of laughter yoga and pilates on their psychological and emotional adaptation to pregnancy. The total study duration for participants is four weeks, with outcomes assessed at the end of this period.

This research aims to study nurses who care for people facing difficult situations such as illness, loss, or being in the final stages of life, focusing on their experiences with death anxiety and death awareness. Nurses may be affected by these situations differently based on factors like their work unit, workload, and personal characteristics. The study recognizes that while death education can help, individual differences in coping with grief are important, and specialized training may better support nurses in managing death-related stress. The study involves a 6-week program consisting of 12 mindfulness-based group psychoeducation sessions designed to increase nurses awareness of death and reduce their anxiety about it. The program covers topics such as the death process and anxiety, the impact on individuals and families, coping methods, effects on nurses providing care, awareness of death, and emotional skills needed during the death process. Nurses will be assigned randomly to an experimental group receiving this education or a control group. Participants will be nurses working in palliative care, emergency, or intensive care units. Data will be collected using questionnaires before and after the program, including scales measuring death awareness and death anxiety. Statistical tests will assess changes in scores, helping to understand if the psychoeducation reduces death anxiety and increases awareness. The study plans to include 36 nurses total and will monitor outcomes four weeks after the program.

Schizophrenia is a long-lasting and disabling condition that impacts quality of life and daily function. Researchers are studying the effects of a mindfulness-based psychoeducation program given individually to people with schizophrenia. This study aims to see if this program can reduce internalized stigma and improve healthy lifestyle behaviors among these patients. The research includes 40 participants from a community mental health center, divided into experimental and control groups, using a pre-test and post-test design.