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Found 18 Actively Recruiting clinical trials

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Actively Recruiting

Healthy Volunteer

This research aims to compare the effects of aromatherapy and music therapy on anxiety levels in children undergoing their first intraoral radiographic examination. Dental anxiety is common in pediatric patients and can affect how well they cooperate during treatment. The study evaluates which intervention, or combination of both, may better reduce anxiety in this setting. Children will be randomly assigned to one of four groups aromatherapy with lavender oil, music therapy with calming music, both aromatherapy and music therapy together, or a control group receiving standard care without extra interventions. Aromatherapy involves diffusing lavender essential oil in the clinical environment, while music therapy uses Pachelbels Canon in D major played at a comfortable volume before the radiographic procedure. Participants will have their anxiety levels measured immediately before and after the panoramic radiography using the Facial Imaging Scale. Pulse rate will also be recorded using a finger pulse oximeter at the same timepoints. Researchers will assess whether these therapies reduce anxiety and heart rate compared to the control group. The study may help develop simple, non-invasive methods to improve comfort and cooperation in children during dental X-rays.

All GendersPhase Not Applicable
1 location
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Actively Recruiting

Healthy Volunteer

Researchers are investigating whether there is a connection between gum disease periodontal disease and chronic neck pain with related functional disability in adults aged 30 to 55 years. The study aims to understand if the severity of gum disease is linked to the intensity of neck pain and the level of disability experienced, potentially highlighting a relationship between oral health and musculoskeletal health. Participants will be grouped based on their gum health status into three categories healthy gums, gingivitis, or periodontitis, classified using clinical examinations and the 2017 World Workshop criteria. Neck pain intensity will be measured using the Visual Analog Scale VAS, while functional disability related to neck pain will be assessed using the Neck Disability Index NDI. This is a cross-sectional observational study, meaning data will be collected at a single time point without administering treatments. During the study, participants will undergo a dental examination including assessments of gingival inflammation, plaque, bleeding, probing depth, and bone loss. They will also complete questionnaires about their neck pain and disability. The researchers will analyze the relationship between gum disease severity and neck paindisability, considering other possible influencing factors. The study is expected to contribute to better understanding the link between oral and musculoskeletal health.

Age: 30Years - 55YearsAll Genders
1 location
E

Actively Recruiting

Researchers are evaluating the effects of an early rehabilitation program combined with neuromuscular electrical stimulation NMES and telerehabilitation on functional recovery in patients undergoing total hip arthroplasty THA. After this surgery, patients often face muscle weakness, difficulty walking, and limited function, which can slow recovery. This prospective, randomized controlled trial aims to determine whether adding NMES and telerehabilitation to early rehabilitation improves recovery outcomes compared to standard care. Participants will be randomly assigned to one of two groups. The intervention group will receive a structured physiotherapy program starting on the first day after surgery and continuing daily during their 5-day hospital stay. This includes NMES targeting the gluteus medius muscle. After discharge, they will continue a 3-week home exercise program supported by supervised telerehabilitation sessions three times per week. The control group will receive routine postoperative care with wound monitoring and a home exercise brochure without supervised rehabilitation or telerehabilitation. Participants will be assessed before surgery, at discharge day 6, and four weeks after surgery. Evaluations include functional tests such as the Timed Up and Go Test, 10-Meter Walk Test, Stair Climb Test, and 6-Minute Walk Test. Muscle strength, joint range of motion, pain levels, gait parameters, quality of life, and muscle changes will also be measured. Assessments will be conducted by blinded physiotherapists. The study will last from before surgery through four weeks postoperatively, with safety and recovery closely monitored throughout.

Age: 50Years - 75YearsAll GendersPhase Not Applicable
1 location
S

Actively Recruiting

Healthy Volunteer

Researchers are studying bruxism, a condition involving teeth grinding, in children aged 10 to 12 years. This study aims to examine clinical signs of bruxism and measure the thickness of the masseter muscle using ultrasound imaging. It also evaluates how wearing a custom-made night guard at night affects these clinical findings and muscle thickness over time. Participants will receive a custom-made night guard designed to be worn during sleep. The study involves a single group of 20 children diagnosed with bruxism based on parents reports and clinical exams. Muscle thickness measurements will be taken on both sides of the face at the start of the study, at 3 months, and again at 6 months. Clinical symptoms like tooth wear, muscle tenderness, jaw joint issues, and habits will be monitored throughout. Children will be assessed at three time points baseline, 3 months, and 6 months. Ultrasonography will be performed using a standardized method by a specialist. Pain levels will be recorded using the Wong-Baker Faces Pain Rating Scale, and jaw joint function will be evaluated by checking for joint sounds, movement deviations, and tenderness. The study is non-invasive, without radiation, and participation lasts about six months.

Age: 10Years - 12YearsAll GendersPhase Not Applicable
1 location
S

Actively Recruiting

Researchers are evaluating the effect of early mobilization training given before cesarean section surgery and a targeted mobilization program applied after surgery. The study aims to see if these interventions can prevent gastrointestinal complications after cesarean delivery and help with breastfeeding and baby care. Increasing cesarean section rates worldwide have made postoperative care more important, but the best way to implement early mobilization is still unclear. This study uses an experimental design to fill this knowledge gap and improve recovery outcomes for mothers. The study includes two groups an intervention group receiving early mobilization education before surgery and a targeted mobilization program afterward, and a control group receiving routine care. The intervention group learns about the benefits of early mobilization, step goals, and how to use a smartphone pedometer and diary to track walking time and steps. The control group will record their walking distance as part of routine care. The study is randomized and open-label, starting with patient education at hospital admission. Participants will complete forms including postoperative gastrointestinal function, abdominal distension diagnosis, pain assessment using a visual analog scale, breastfeeding evaluation using the LATCH scale, and other breastfeeding information. Data collection occurs over three months. Researchers will analyze these outcomes to assess the impact of the mobilization program on recovery, breastfeeding participation, and gastrointestinal health after cesarean section. The study is sponsored by Nigde Omer Halisdemir University and runs until April 2025.

Age: 18Months - 35YearsFEMALEPhase Not Applicable
1 location
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Actively Recruiting

Healthy Volunteer

Researchers are evaluating the effect of an education program based on Roys Adaptation Model on how adults with asthma adjust socially and psychologically to their disease and how it affects their quality of life. The study focuses on individuals aged 18 to 64 years who have asthma with partial or uncontrolled symptoms and no other chronic diseases. The goal is to improve patients attitudes and behaviors toward managing asthma through planned and repeated training to empower them during their disease process. Participants are randomly assigned to one of two groups. One group receives the asthma education program based on the Roy Adaptation Model alongside their standard asthma treatment, while the other group continues with standard asthma treatment only. This is a single-blind randomized controlled trial designed to compare the outcomes between these two approaches over a 12-week period. During the study, participants will be assessed on their psychosocial adjustment to asthma using the Psychosocial Adjustment To Illness-Self-Report Scale PAIS-SR and their quality of life using the Asthma Quality of Life Questionnaire AQLQ. These assessments will take place from enrollment through the end of treatment at 12 weeks. The study aims to monitor changes in these outcomes to understand the impact of the education program on managing asthma.

Age: 18Years - 64YearsAll GendersPhase Not Applicable
1 location
S

Actively Recruiting

Healthy Volunteer

Researchers are investigating differences in gingival crevicular fluid GCF biomarker profiles between children and young adults with gingivitis. This observational case-control study involves approximately 80 healthy participants divided into two groups children aged 8 to 12 years and young adults aged 15 to 24 years. The study excludes individuals aged 13 to 14 years due to hormonal changes during puberty that may affect inflammatory markers. The goal is to better understand age-related variations in gingival inflammation and biomarker expression. Participants will undergo clinical periodontal examinations measuring gingival index, plaque index, bleeding on probing, and probing depth. GCF samples will be collected from a specific tooth 31 using sterile paper strips and analyzed for inflammatory and anti-inflammatory markers IL-1, TNF-, IL-10, and MMP-8 using enzyme-linked immunosorbent assay ELISA. The collection procedure is non-invasive and performed solely for biomarker analysis. Throughout the study, participants will have their clinical periodontal parameters recorded and provide GCF samples at baseline. Researchers will compare cytokine levels and periodontal health indicators between the two age groups. The study may help clarify how hormonal transitions influence gingival inflammation during childhood and early adulthood. Participation involves cooperation during sample collection and examination, with no treatment interventions applied.

Age: 8Years - 24YearsAll Genders
1 location
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Actively Recruiting

Healthy Volunteer

This research aims to explore how fathers involvement in caring for their infants aged 4 to 6 months relates to the infants sensory processing abilities. It addresses a gap in knowledge about the impact of fathers active participation on infant development, focusing specifically on sensory skills. The study is observational and involves healthy, full-term infants and their families to understand this relationship better. Fathers involvement will be evaluated using a specialized questionnaire that measures the level of caregiving activities by fathers. Mothers will complete the Infant Sensory Profile-2 questionnaire to assess their infants sensory processing patterns. These tools help researchers understand both the fathers participation and the infants developmental responses during the 4 to 6 month age period. Participants will be asked to complete questionnaires about the fathers involvement in caregiving and the infants sensory behaviors. The study measures include the Fathers Involvement in Infant Care Questionnaire and the Infant Sensory Profile-2. Data collection focuses on parent-reported information without any treatment interventions. The study is planned to start in May 2026 and conclude by March 2027, involving healthy infants born at full term and their families.

Age: 4Months - 6MonthsAll Genders
1 location
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Actively Recruiting

Healthy Volunteer

This research aims to evaluate how breastfeeding education provided to grandparents during the prenatal period influences mothers motivation, confidence, and continuation of exclusive breastfeeding. Breastfeeding is essential for newborn nutrition, yet rates of breastfeeding within the first hour and exclusive breastfeeding for six months are below global recommendations. Grandparents, especially grandmothers, often play a key role in supporting or influencing breastfeeding practices, but their impact can be both positive and negative. The study compares three groups one receiving structured breastfeeding training for grandmothers, another receiving similar training for fathers, and a control group with routine institutional care without training. Education focuses on improving support for breastfeeding initiation and maintenance. The interventions occur during pregnancy, aiming to affect breastfeeding behavior postpartum. Participants will be monitored from late pregnancy through postpartum days 7, 20, and 40. Researchers will assess breastfeeding self-efficacy, motivation, and breastfeeding status using validated scales. The study will collect data on mothers confidence and breastfeeding continuation, with all participants followed until 40 days after birth to evaluate outcomes and support breastfeeding promotion efforts.

Age: 18Years - 35YearsAll GendersPhase Not Applicable
1 location
S

Actively Recruiting

Healthy Volunteer

Researchers are studying infants aged 6 to 18 months with primary congenital hypothyroidism, a condition where the thyroid gland is underactive or absent. This condition can affect brain development, leading to cognitive and motor challenges despite early hormone treatment. The study aims to explore neurological status, motor skills, and sensory processing abilities during this critical early stage of brain development called synaptogenesis. The goal is to better understand how congenital hypothyroidism impacts these developmental areas to support early follow-up and intervention. The study compares infants diagnosed and treated for primary congenital hypothyroidism with a control group of healthy infants born at term. Assessments include the Hammersmith Infant Neurological Examination to evaluate neurological status, the Test of Sensory Function in Infants to assess sensory processing, and the Peabody Developmental Motor Scales-2 to measure motor development. These tests are standardized and designed for infants within the studys age range. Participants will undergo developmental and neurological evaluations between 6 and 18 months of age. Researchers will collect data on motor skills, sensory abilities, and neurological health through these assessments. The study may help establish scientific evidence for early monitoring and intervention programs. The total participation period aligns with the infants ages from 6 to 18 months, focusing on early detection of developmental differences.

Age: 6Months - 18MonthsAll Genders
1 location

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