Nigde Merkez

Researchers are evaluating how aromatherapy and music therapy affect anxiety levels in children undergoing their first intraoral radiographic dental examination. This study focuses on pediatric dental anxiety, which can interfere with cooperation and treatment success. The goal is to find simple and non-invasive ways to ease children's anxiety during dental X-rays. Children will be randomly assigned to one of four groups: aromatherapy with lavender oil, music therapy with calming music (Pachelbel's Canon in D major), a combination of both aromatherapy and music, or a control group receiving standard care without these interventions. Aromatherapy is delivered through an aroma diffuser before the X-ray, and music therapy is played via speakers at a comfortable volume. Anxiety will be measured immediately before and after the radiographic procedure using the Facial Image Scale (FIS). Pulse rate will also be recorded using a finger pulse oximeter at the same times. The study aims to determine which approach most effectively reduces anxiety in children during dental radiography.

Researchers are evaluating the effects of an early postoperative rehabilitation program combined with neuromuscular electrical stimulation (NMES) and telerehabilitation on functional recovery in patients undergoing total hip arthroplasty (THA). Early after surgery, patients often face muscle weakness, walking difficulties, and limited function that can slow recovery. This study aims to determine if adding NMES and telerehabilitation to early rehabilitation improves outcomes compared to standard care. Participants are randomly assigned to either an intervention group or a control group. The intervention group receives a daily structured physiotherapy program starting the first day after surgery, combined with NMES applied to the gluteus medius muscle for 5 days during hospitalization. After discharge, this group continues a 3-week home-based exercise program supported by video telerehabilitation sessions three times weekly. The control group receives routine postoperative care without NMES or telerehabilitation, including wound monitoring and a home exercise brochure. Participants will be assessed before surgery, at discharge on postoperative day 6, and four weeks after surgery. Evaluations include functional tests such as the Timed Up and Go Test, 10-Meter Walk Test, and Stair Climb Test. Muscle strength, joint mobility, pain, gait, and muscle structure will also be measured. Assessments are done by blinded physiotherapists, and the study monitors recovery progress, safety, and any complications during the follow-up period.

Researchers are evaluating the clinical signs of bruxism and the thickness of the masseter muscle in children aged 10 to 12 years. The study aims to observe how using a night guard affects these signs and muscle thickness over time. The focus is on children diagnosed with bruxism based on reports from parents and clinical examinations, without including a control group. Participants will receive a custom-made night guard designed to be worn regularly during sleep. The masseter muscle thickness will be measured on both sides of the face using ultrasonography at the start of the study, after 3 months, and again at 6 months. Clinical signs such as tooth wear, muscle tenderness, temporomandibular joint findings, and parafunctional habits will also be recorded throughout the study. Children will be assessed at three different times to track changes in muscle thickness and bruxism symptoms. Ultrasonography will be performed by an experienced radiologist using a standardized method. The study involves no invasive procedures or radiation exposure. Participants will be monitored over a total of 6 months to evaluate the effects of night guard use on their condition.

Researchers are evaluating the effect of early mobilization training given before cesarean section surgery and a targeted mobilization program applied after surgery on preventing gastrointestinal complications and supporting participation in breastfeeding and baby care. The study addresses the increasing rates of cesarean sections worldwide and the need for improved postoperative care to reduce complications such as delayed bowel movements, wound healing issues, and difficulties in baby care. This randomized controlled study aims to provide scientific evidence on the optimal timing, frequency, and structure of early mobilization programs for women undergoing cesarean delivery. Participants receive early mobilization training before surgery, which explains the importance of mobilization, its benefits, and the goals set for each patient. After surgery, patients follow a targeted mobilization program that includes walking and using a smartphone pedometer app to track steps and walking time. Patients in the intervention group keep a mobilization diary to record their activity and any positive or negative experiences during mobilization. This approach encourages daily written goals and nurse involvement to support early mobilization. During the study, data are collected using forms on postoperative gastrointestinal function, abdominal distension, pain levels (VAS), breastfeeding evaluation, and baby care participation. Researchers will analyze these data using statistical software to assess the effects of the mobilization program. The study includes follow-up assessments up to three months post-surgery, monitoring gastrointestinal recovery, pain, and breastfeeding outcomes. Participants’ adherence to mobilization is tracked through diaries and pedometer data, with safety and complications monitored throughout the study period.

This research aims to evaluate the effect of an education program based on Roy's adaptation model on the psychosocial adjustment and quality of life of adults diagnosed with asthma. The study focuses on individuals aged 18 to 64 years who have had asthma for at least six months and experience partial or uncontrolled asthma as measured by the Asthma Control Test (ACT). The goal is to improve patients' behaviors toward managing their chronic condition, thereby enhancing their adaptation and overall well-being. Participants receive an asthma education program built around the Roy Adaptation Model alongside their standard asthma treatment. This program involves regularly repeated training sessions designed to improve adaptive behaviors and empower individuals to better control their asthma and manage the disease process. The intervention is compared to standard treatment in this randomized controlled trial. Throughout the 12-week study period, researchers assess participants' psychosocial adjustment using the Psychosocial Adjustment To Illness-Self-Report Scale (PAIS-SR). The study includes evaluations of quality of life and asthma control, with ongoing monitoring to understand how education influences adaptation to the disease. Participants are involved in regular assessments to track changes from enrollment until the end of the treatment phase.

Researchers are evaluating how dim light exposure during active labor affects pain, anxiety, and the progress of labor in pregnant women at term. The study focuses on women aged 18 to 45 years who have a single baby in the head-down position and are in active labor. The purpose is to see if lowering light levels in the labor room can improve comfort and labor outcomes compared to usual room lighting, addressing a gap in high-quality evidence about lighting's impact on childbirth experience. Participants are randomly assigned to one of two groups. One group gives birth in a room with dim lighting maintained between 50 and 80 lux using warm white or amber light sources, monitored regularly with a lux meter. The other group receives standard labor room lighting as part of routine care. If needed for safety or clinical reasons, room lighting can be increased immediately. Both groups receive all usual obstetric care according to hospital protocols. During labor, pain and anxiety levels are measured at specific times using validated scales. Researchers also record labor duration, use of medications to assist labor, delivery type, and newborn outcomes from clinical records. The primary outcome focuses on pain intensity changes over the first 120 minutes of active labor. Data are collected prospectively, kept confidential, and the trial is conducted under ethical approval. This study may help determine if a simple change in lighting can enhance the childbirth experience.

The trial investigates infants with primary congenital hypothyroidism, a condition where the thyroid gland is underactive or absent at birth. This condition can affect brain development, causing cognitive and motor challenges despite early treatment. The study aims to explore neurological status, motor development, and sensory processing skills in infants aged 6 to 18 months, addressing gaps in current research, especially in early life stages. Understanding these developmental areas may provide a foundation for early intervention programs. Researchers will assess infants using three main tools: the Hammersmith Infant Neurological Examination (HINE) to evaluate neurological status, the Test of Sensory Function in Infants (TSFI) to examine sensory processing skills, and the Peabody Developmental Motor Scales-2 (PDMS-2) to measure motor development. Each test is designed for infants within the 6 to 18 months age range and helps identify developmental delays or neurological issues. Participants will be evaluated between 6 and 18 months of age. Assessments will include neurological exams, sensory function tests, and motor skill evaluations. These measures aim to track motor, sensory, and neurological development over time. The study focuses on infants treated for primary congenital hypothyroidism from birth and born at term, with the objective to better understand developmental outcomes and support early care strategies.

This research aims to evaluate how providing information and practicing progressive relaxation exercises before planned cesarean section surgery affect surgical fear, anxiety, postpartum comfort, and pain levels in first-time pregnant women. The study focuses on women aged 18 to 35 who are scheduled for a planned cesarean with spinal anesthesia and have a single live pregnancy. It addresses the high rates of cesarean sections globally and the common experience of fear and anxiety among women undergoing this surgery, which can impact recovery and satisfaction with the birth experience. Participants will be involved in progressive relaxation exercises and receive education before their cesarean section. The study compares outcomes related to fear, anxiety, comfort, and pain by using these non-drug methods aimed at reducing psychological distress. These exercises involve systematically tensing and relaxing muscle groups to help women achieve bodily and mental relaxation before surgery. Throughout the study, various assessments such as the State Anxiety Scale, Surgical Fear Scale, and Postpartum Comfort Scale will be used to measure anxiety, fear, comfort, and pain levels. Data will be collected using forms and questionnaires, then analyzed with statistical software. Participants will be monitored to evaluate the impact of the interventions on their psychological and physical wellbeing during and after cesarean delivery.

Multiple Sclerosis (MS) is a common chronic inflammatory disease affecting young adults aged 20 to 40 years, causing irreversible neurological damage. This research aims to compare the effects of intermittent fasting and the Mediterranean diet on quality of life, sleep, circadian rhythm, and appetite hormones leptin and ghrelin in women with MS. It addresses a gap in the literature where these diets have not been evaluated together for their impact on these parameters in MS patients. Participants will follow either an intermittent fasting or Mediterranean diet program as part of the study. The dietary interventions are applied to assess their effects on the listed health outcomes over a period of time. The study focuses on female patients aged 18 to 65 years who have a confirmed diagnosis of MS and are not in an attack period or menopause. During the study, researchers will measure biochemical parameters from baseline to 3 months to evaluate changes. Participants will undergo assessments including quality of life, sleep patterns, circadian rhythm, and hormone levels related to appetite. The study also involves brain MRI scans within the last three months and monitoring of body mass index and weight stability. Safety monitoring includes excluding those with other autoimmune diseases, eating disorders, or physical disabilities. The total duration of participation involves adherence to the diet programs and evaluation over three months.

This research aims to evaluate whether a special wound dressing containing ozonated oil can reduce early wound inflammation after open inguinal hernia surgery. Open inguinal hernia repair is a common surgery, and while infection rates are low, many patients experience redness, swelling, tenderness, or discomfort at the surgical site in the first days after the operation. The study focuses on early wound inflammation rather than infection, using a composite clinical and photographic inflammation score assessed by blinded evaluators to measure outcomes. Participants scheduled for elective, unilateral open inguinal hernia repair will be randomly assigned to receive either an ozonated oil-impregnated sterile gauze dressing applied immediately after skin closure or a standard sterile dry dressing. The ozonated oil dressing is changed once daily for the first 48 hours postoperatively, followed by standard wound care. The standard dressing is removed within 24 to 48 hours post-surgery, with subsequent wound care continuing according to routine practice. During the study, researchers will assess wound inflammation on the third day after surgery, including wound temperature, pain levels, cosmetic healing, and any wound-related problems during the first 30 days. Wound surface temperature will be measured using a non-contact infrared thermometer. The study aims to provide preliminary data on the feasibility and effects of ozonated oil dressing to guide future larger studies. Safety and infection-related outcomes will also be collected for exploratory purposes.