Optimizing Low-dose Contrast Media Protocol for Low-kVp Abdominopelvic CT in Suspected Acute Appendicitis

What this Trial Is About

This research aims to evaluate the use of low radiation dose abdominal CT combined with low dose contrast media to diagnose acute appendicitis in young patients. The main goals are to determine if this low-dose method can provide accurate diagnosis and how much radiation exposure can be reduced compared to standard CT scans. The study focuses on patients suspected of having acute appendicitis who are evaluated in the emergency department. Participants receive a weight-adjusted low-dose contrast media along with a low-radiation dose abdomen CT scan. The contrast media dose varies based on the CT device's automatic selection of the kVp value according to body size, aiming for a reduction in iodine dose by 10% to 30% depending on the kVp setting. The low-dose CT and contrast media protocol is designed to maintain diagnostic quality while lowering radiation and iodine exposure. During the study, participants will undergo the CT scan with this specialized low-dose protocol. Researchers will assess diagnostic accuracy for acute appendicitis, following operated patients for up to one month after surgery and non-operated patients for six months. The study includes monitoring for safety and effectiveness of the imaging method, with total participation time depending on patient treatment and follow-up visits.

Low-dose Contrast Media for Low-kVp Abdomen CT