Study of Immune Cells in Lung Tumors in Adults Having Surgery A Monocentric Observational Study at San Raffaele Institute

What this Trial Is About

Researchers are conducting a monocentric observational study to explore the molecular structure of tumors in the thoracic cavity, focusing on non-small cell lung cancer NSCLC. The study aims to better understand the lymphocytic infiltrate within lung tumors by collecting clinical data and biological samples from patients diagnosed with thoracic tumors. Participants will be patients over 18 years old who are candidates for surgical treatment of thoracic tumors. During hospitalization and surgery, clinical data and biological material such as blood and tumor tissue will be collected. There is only one hospital visit for these procedures, and no follow-up data collection after discharge. The study is planned to last three years. During the single hospital visit, participants will undergo standard clinical procedures related to their treatment. Researchers will isolate lymphocytes within 15 days from enrollment to surgery and analyze lymphocyte gene expression within 48 hours after surgery. The study focuses on detailed biological analysis without further interventions, and participant observation is limited to the surgery period.

The Lymphocytic Infiltrate of Lung Tumors.