Evaluation of Pregnancy Outcomes After Medically Assisted Fertilization in Women With Systemic Autoimmune Rheumatologic Diseases

What this Trial Is About

Researchers are studying the effects of medically assisted fertilization techniques in women with systemic rheumatological diseases, such as Systemic Lupus Erythematosus SLE and Anti-Phospholipid Antibody Syndrome APS. The study aims to evaluate how these treatments impact the underlying disease activity and the outcomes of assisted reproductive techniques ARTs, particularly in women of childbearing age who might be affected by these conditions. Participants undergo standard ovarian stimulation treatments using various types of gonadotropins and hormone therapies to prepare for egg retrieval. The fertilization process may involve in vitro fertilization IVF or intracytoplasmic sperm injection ICSI. Hormonal support is provided during embryo transfer. The study records detailed information about the treatments used and the choices made during the fertility procedures. Throughout the study, researchers will collect data on patients clinical and laboratory tests, treatment details, and pregnancy outcomes, including any complications or disease flare-ups. The primary focus is to measure the risk of disease reactivation and complications within six months following the assisted reproduction procedures and pregnancies. Participant involvement includes monitoring and follow-ups to assess maternal and fetal health during and after pregnancy.

Medically Assisted Fertilization Techniques in Systemic Immunoreumatologic Diseases