Actively Recruiting

Age: 18Years +
All Genders
NCT05099315

Microbiome in Atopic Dermatitis Under Systemic Therapy

Led by Charite University, Berlin, Germany · Updated on 2025-02-13

600

Participants Needed

1

Research Sites

326 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The skin microbiome plays a role in the pathogenesis of atopic dermatitis. However, it is unclear whether the range of microbiota on the skin is the cause or consequence of atopic skin inflammation. The influence of new systemic therapies for the treatment of moderate to severe atopic dermatitis (such as biologics or Janus kinase inhibitors) on the skin microbiome is largely unknown. The main aim of this scientific exploratory study is to investigate whether and how the skin microbiome changes in patients with moderate to severe atopic dermatitis during systemic therapy. This not only allows new hypotheses to be generated on the pathogenesis of atopic dermatitis, but also new objective scales for the severity of atopic dermatitis can be developed.

CONDITIONS

Official Title

Microbiome in Atopic Dermatitis Under Systemic Therapy

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with moderate to severe atopic dermatitis
  • Indication for systemic therapy
Not Eligible

You will not qualify if you...

  • Patients under 18 years of age upon introducing systemic therapy
  • Pregnant and lactating women

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Dpt of Dermatology and Allergology, Charité - Universitätsmedizin Berlin

Berlin, State of Berlin, Germany, 10117

Actively Recruiting

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Research Team

M

Margitta Worm, Prof

CONTACT

S

Sabine Dölle-Bierke, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

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