Actively Recruiting
Microfluidic Chip vs Density Gradient Centrifugation on the Euploidy Rate of Pre-implantation Genetic Testing
Led by Professor Ernest Hung-Yu Ng · Updated on 2024-12-06
318
Participants Needed
1
Research Sites
212 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Infertile women attending for PGT at the Centre of Assisted Reproduction and Embryology, Queen Mary Hospital and Kwong Wah Hospital will be recruited during ovarian stimulation for IVF. Subsequently, they will be randomly assigned on the day of oocyte retrieval by a laboratory staff into one of the following two groups in a 1:1 ratio : (1) the microfluidic chip group and (2) the density gradient centrifugation group for sperm preparation and subsequent use in fertilization. Other IVF procedures will be the same as the standard practice of the Centre. Both women and clinicians will be blinded from the group allocation i.e. a double blind study.
CONDITIONS
Official Title
Microfluidic Chip vs Density Gradient Centrifugation on the Euploidy Rate of Pre-implantation Genetic Testing
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Women aged less than 43 years at the time of ovarian stimulation for IVF
- Women undergoing preimplantation genetic testing for monogenic diseases, chromosomal rearrangements, or aneuploidy
- Raw semen sperm concentration with at least 0.15 million motile sperm per ml or 100 motile sperm per 50 low power fields (200x)
You will not qualify if you...
- Use of frozen semen for insemination
- Use of donor eggs or sperm
- Presence of submucosal fibroid or hydrosalpinx shown on pelvic scan and not surgically treated
- Women who have participated in this study before
- Women currently enrolled in other randomized trials
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Department of Obstetrics and Gynaecology
Hong Kong, Hong Kong, China
Actively Recruiting
Research Team
Y
YU WING TONG, MBBS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here